Tag Archives: tuberculosis

Alarming Levels of Drug-Resistant Tuberculosis in HIV-Infected Patients in Metropolitan Mumbai, India

India is a high burden country for tuberculosis (TB) and multidrug-resistant TB (MDR-TB). The World Health Organization has estimated that India accounted for 26% of the total number of TB cases worldwide in 2012, with…

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Mycobacterium tuberculosis Modulates the Gene Interactions to Activate the HIV Replication and Faster Disease Progression in a Co-Infected Host

Mycobacterium tuberculosis (Mtb) continues to be one of the most dreaded pathogens around the world and its co-habitation with HIV in a common host fuels both the infections. Of the estimated 39 million people living with HIV, about one-third are estimated to have concomitant latent tuberculosis (Global Tuberculosis Control, WHO, 2010). Depending on the prevalence of HIV…

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Impact of Introducing the Line Probe Assay on Time to Treatment Initiation of MDR-TB in Delhi, India

Among patients with multidrug resistant- tuberculosis (MDR-TB), delays in diagnosis and treatment initiation are frequently observed, resulting in an increased risk of disease complications and high mortality and pre-treatment lost to follow-up rates.

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Incidence of Active Pulmonary Tuberculosis in Patients with Coincident Filarial and/or Intestinal Helminth Infections Followed Longitudinally in South India

Mycobacterium tuberculosis (Mtb) infection remains a disease of significant public health importance, particularly in resource-limited parts of the world. According to WHO reports, 1·4 million deaths were associated with tuberculosis (TB) in 2010 worldwide.[1], [2] The 2010 worldwide tuberculosis (TB) incidence was 8·8 million (128 cases/100 000 inhabitants), of which 59% were detected in Asia.

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Profile and Response to Anti-Tuberculosis Treatment among Elderly Tuberculosis Patients Treated under the TB Control Programme in South India

The demographic transition in India has resulted in the label of an ageing nation [1]. The Government of India’s ‘National Policy on Older Persons’ defines ‘elderly’ as a person who is of age 60 years or above [2]. In 2001, the proportion of elderly in India was about 7.4% of the overall population which increased to 8.3% in 2011.

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Tuberculosis Management Practices of Private Practitioners in Pune Municipal Corporation, India

According to the third National Family Health Survey in India, conducted in 2006, the private sector remains a primary source for health care for patients of all socioeconomic levels [1]. A large proportion of patients with tuberculosis (TB) in countries with high TB prevalence first seek care with a private practitioner.

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Do We Need to Detect Isoniazid Resistance in Addition to Rifampicin Resistance in Diagnostic Tests for Tuberculosis?

Globally, tuberculosis (TB) occurs in about 9 million people, and kills about 1.4 million every year [1]. Although progress has been made in increasing TB cure rates, drug resistance is of increasing concern in most parts of the world. The current cornerstone of TB diagnosis (smear microscopy) does not detect drug resistance, but novel molecular tests offer…

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