While reducing the risk of classic fracture, treatment with bisphosphonates may increase the risk of atypical fractures of the femur, with a longer duration of treatment linked to this increasing risk, according to a new study. “We have demonstrated that the association between bisphosphonate treatment and the occurrence of atypical…
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Adding a second antihypertensive medication appears to be more beneficial than increasing the dose of a single antihypertensive in reducing all-cause mortality cardiovascular outcomes in patients with cardiovascular disease (CVD). This was the main finding of a recent randomized trial that sought to determine the efficacy of high-dose angiotensin receptor…
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The investigational antibiotic delamanid increased 2-month sputum-culture conversion in patients with multidrug-resistant pulmonary tuberculosis (TB). This was the main finding of a recent randomized, placebo-controlled trial that sought to determine the efficacy and safety of delamanid added to standard therapy vs standard therapy alone in this population. Key Point: Delamanid,…
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Postmenopausal women with type 2 diabetes that requires treatment with insulin demonstrated an increased risk for developing lung cancer, according to an analysis of the Women’s Health Initiative (WHI) study. “Physicians in India should screen diabetes patients, especially women, for lung cancer, particularly those on insulin therapy.” -Vijay Viswanathan, MD,…
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Neuropathy is a common, disabling complication of diabetes, and its incidence in India is growing as the prevalence of diabetes—especially type 2 diabetes—continues to rise nationally. India has the world’s largest diabetic population, with an estimated 62 million people diagnosed with the condition, according to the Indian Council of Medical…
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Due to difficulties in establishing accurate diagnoses and lower priorities assigned by tuberculosis (TB) control programs, pediatric TB has been relatively neglected. Treatment delays lead to the progression of disease, increased risk of infectiousness, greater complications, and higher rates of morbidity and death. “The key learnings identified from this study…
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New-generation anticoagulant agents pose risks in treatment of acute coronary syndromes
The potential ischemic benefits of novel oral antiplatelet therapy following an acute coronary syndrome (ACS) may be offset by a significant increase in major bleeding events, according to a meta-analysis recently published in the Archives of Internal Medicine. “We are already exposing these patients to several drugs that can produce…
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