As a disease of poverty and inequity, cholera is often prevalent in areas of compromised sanitation, overcrowded conditions, and poor quality of water supply. An increasing number of longer lasting outbreaks have dramatically impacted the least developed countries (LDCs), including those in Africa, South Asia, and the Hispaniola island region. Living conditions in LDC populations often favor…
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Potential for Controlling Cholera Using a Ring Vaccination Strategy
The current prequalified oral cholera vaccines provide over 80% (direct) protection in the first 6 mo after vaccination, with protection of up to 65% for 5 y estimated in an endemic settin. However, this estimate does not include herd protection…
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