Type 2 diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia. The key pathophysiologic abnormalities that have been associated with the disease are decreased peripheral glucose utilization combined with…
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Diabetes Mellitus is a heterogeneous syndrome of abnormalities in carbohydrate and fat metabolism, characterized by multi-factorial interplay between genetic and environmental factors culminating into…
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Gestational diabetes (GDM) was historically defined as ‘any degree of glucose intolerance with onset or first recognition during pregnancy’. The incidence of GDM is rising globally and it represents an important modifiable risk factor for adverse pregnancy outcomes such as…
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Early screening of type 2 diabetes mellitus (DM) is essential for improved prognosis and effective delay of clinical complications associated with diabetes, and has been suggested as an important strategy to lower the incidence of this disease worldwide [1]–[3]. To date, urine and blood tests are available for screening type 2 DM.
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Fasting plasma glucose (FPG) and glycated hemoglobin (HbA1C) are the central measures of diagnosis of Type 2 diabetes (FPG ≥126 mg/dl (7.0 mmol/L); HbA1C ≥6.5%) and prediabetic states (FPG 100–125 mg/dl (5.5–6.9 mmol/L); HbA1C 5.7–6.4%). The clinical management of diabetes focuses on the control of hyperglycemia using a combination of nutritional and pharmacological therapies.
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Metabolic syndrome is a known risk factor for cardiovascular disease, diabetes, and cancer. The diagnosis is made based on the presence of 3 or more of the following clinical signs: waist circumference of 88 cm or more; serum triglycerides of 1.7 mmol/L or more; blood pressure of 130/85 mmHg or…
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Plaque Characteristics in Coronary Artery Disease Patients with Impaired Glucose Tolerance
In addition to diabetes mellitus, which is established as one of the most significant risk factors of coronary artery disease, prediabetic conditions such as impaired glucose tolerance have been also reported to increase the…
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