The potential ischemic benefits of novel oral antiplatelet therapy following an acute coronary syndrome (ACS) may be offset by a significant increase in major bleeding events, according to a meta-analysis recently published in the Archives of Internal Medicine. “We are already exposing these patients to several drugs that can produce…
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A healthful diet and exercise have a significant positive effect on serum lipid profiles, and obesity constitutes a major risk factor for the development of hypercholesterolemia and hypertriglyceridemia, a recent Indian-based study found. Key Point: A healthful diet and regular exercise are effective reducing the risk of cardiovascular disease. Prevention…
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A 5-day course of azithromycin is associated with an increased risk of cardiovascular death, according to a recently published retrospective cohort study. Key Point: Azithromycin appears to have an adverse cardiac effect, possibly as a result of being proarrhythmic. The risk:benefit profile should be carefully considered before prescribing this agent,…
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Chronic use of low-dose aspirin, defined as 300 mg/day or less, is associated with an increased risk of major gastrointestinal (GI) or cerebral bleeding, a recent review of administrative data found. Patients with diabetes also were found to have a high rate of bleeding, irrespective of aspirin use. Key Point:…
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Researchers have found that so-called cardiovascular “polypills” may be effective as primary therapy to prevent cardiovascular disease (CVD) in patients aged 50 years and older. “This is an important study but should not be considered as proof of concept, as the authors themselves have acknowledged several limitations, including lack of…
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Elevated plasma homocysteine levels (hyperhomocysteinemia) are increasingly considered to be an important marker for cardiovascular disease (CVD), especially in Indians. The relevance of this finding is highlighted by reports that suggest mortality attributable to CVD is rising in India—and is expected to continue to rise—by 103% in men and by…
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Landmark Trial in Tamil Nadu Reduces Mortality Due to Heart Attack – TN STEMI Program Shows the Way Forward for a National Heart Attack Program
India is a large country with a very high burden of non-communicable disease, particularly cardiovascular diseases. It is estimated that there are over 60 million patients with heart disease in India with…
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