Study finds no increased risk of miscarriage with NSAID use

Women of child-bearing age commonly take over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) for occasional aches and pains. They are also the most common medications women take during the first trimester of pregnancy. In a recent study, women who used common nonprescription NSAIDs (aspirin, ibuprofen, naproxen) in early pregnancy were not found to have an increased risk of spontaneous abortion.

“This study finds that NSAIDs, whether purchased over-the-counter or prescribed for short duration during early pregnancy, do not increase the incidence of spontaneous abortion. However, when used in the second trimester for a longer duration, there is increased risk of failure to close ductus arteriosus.”
-Dhiraj Gada, MD, DGO, DFP, FICMCH, director of Gada Life ART Center, Indore, India

A survey of doctors in Mumbai, India, found that the most commonly prescribed NSAIDs were...

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