Hypothermia treatment decreases mortality of neonatal encephalopathy patients without increasing severe disability

Neonatal hypoxic-ischemic encephalopathy is associated with increased mortality and severe motor or sensory disabilities. Hypothermia is recommended as a treatment option for moderate-to-severe neonatal encephalopathy.

In a new study, United States-based researchers extended a randomized trial of whole-body hypothermia treatment of neonatal encephalopathy to assess the intelligence quotient (IQ) and neurologic disabilities of the 190 evaluable, surviving patients at ages 6 to 7 years. Patients who had received hypothermia treatment as neonates had a death rate of 28% by age 6 to 7 years as compared with 44% in the control group (P=.04), with a combined death or severe disability rate of 41% and 60% for the hypothermia and control groups, respectively (P=.03).


Hypothermia treatment for neonatal hypoxic-ischemic encephalopathy “needs to be practiced in the setting of a neonatal intensive care unit and not in peripheral areas."
-Niranjan Thomas, MD, DCH, DNB, MBBS, professor of Neonatology, Christian Medical College Hospital, Vellore, India


Of the surviving children, there were...

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This entry was posted in Neurology, Pediatrics, Primary Care and tagged , , , , , , . Volume: .

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