Doxycycline may provide significant protection against Clostridium difficile infections

Hospitalized patients who receive doxycycline in addition to ceftriaxone have a 79% reduced risk of Clostridium difficile infection vs patients who receive ceftriaxone only, a recent study found.

"In India, the true prevalence of [C. difficile] is not known because a majority of the hospitals do not investigate for this disease due to lack of awareness and/or due to unavailability of facilities."
-Chetana Vaishnavi, PhD, professor of microbiology at the Postgraduate Institute for Medical Education and Research, Chandigarh, India

The results of this United States-based study suggest that doxycycline may be a valuable agent in combination therapy for first-line treatment for appropriate infections requiring antibiotics, including...