Neurology Articles

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Using the revised diagnostic criteria for frontotemporal dementia in India

The behavioural variant of frontotemporal dementias (bvFTD) is characterized by personality and behavioural changes with relative preservation of episodic memory and visuospatial function. Since 1998, the Consensus criteria have been the cornerstone of diagnosis for bvFTD. [1] The criteria require fulfilment of all of five core diagnostic features at presentation and have a diagnostic specificity of 90–100%. Read more »
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Lifetime Prevalence and Factors Associated with Head Injury among Older People in Low and Middle Income Countries

Traumatic brain injury is a major global public health problem, with around 1.7 million cases recorded annually in the USA alone, corresponding to approximately 0.5% of the country's population. TBI is generally defined as... Read more »

Portable monitoring and feedback device for lower limb performance training

Editor’s note: mdCurrent-India Editors will alert you to promising new therapeutic technologies that we find around the world that might be appropriate for your practice. An important part of therapy for neurological disorder patients is physical therapy to improve motor function and mobility. Neurological disorder patients often suffer from certain...  Read more »

Basics of neurological disorders for primary care physicians

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Neurological disorders include structural, biochemical, or electrical abnormalities in the brain, spinal chord, or the nerves leading to or from them, resulting in a wide range of debilitating symptoms. Neurologic disability is on the rise and may be considered a “hidden” epidemic for India, soon to join the burden of...  Read more »

Antibiotics for treating acute ischemic stroke—a novel idea?

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Minocycline 200 mg once daily taken at the time of first stroke symptoms may aid in improving clinical deficits following an acute ischemic stroke (AIS), but more robust and better controlled clinical studies are needed before the antibiotic can be recommended for this indication. “There is an urgent need to...  Read more »

Study finds high risk of recurrence in Indian patients with transient ischemic attack and minor ischemic stroke

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A recent study in India tracked the short-term risk of additional events in patients who experienced transient ischemic attacks (TIAs) and minor ischemic strokes (MISs). TIAs and MISs, cerebrovascular events that are not acute, are associated with a risk of recurrence or deterioration. “This is the first Indian data on...  Read more »

Apixaban reduces stroke rates in atrial fibrillation patients with previous stroke or TIA

In a subset of patients that had experienced a previous stroke or transient ischemic attack (TIA), treatment with the investigational drug apixaban resulted in a reduced rate of stroke and systemic embolism compared with warfarin, according to a recent subset analysis of a major clinical trial. Stroke is the third-leading...  Read more »

Lipid levels not associated with symptomatic intracranial hemorrhage risk

The World Health Organization (WHO) estimates that about 1.5 million cases of new stroke occur in India each year, resulting in a loss of over 6 million disability-adjusted life-years (DALYs) annually. In a new multicenter, post-hoc analysis of patient registries including more than 1,800 ischemic stroke suffers treated with intravenous...  Read more »

White matter brain injuries in infants may predict altered childhood cognitive function

Giving preterm infants qualitative MRIs when they reach term-equivalent age may help predict cognitive impairments as late as age 9, according to a study published in the journal Pediatrics. The study found that white matter injury found at 38 weeks to 42 weeks was correlated with altered cognitive function at...  Read more »

Zinc supplementation improves cognition in adolescent girls

Adolescent girls who received zinc supplementation through ingesting foods high in zinc or by taking a zinc nutraceutical demonstrated improved cognition and taste acuity, according to an intervention trial conducted in Maharashtra state of Western India. “Zinc has a role in many body functions,” said Anuradha Khadilkar, MD, DCH, associate...  Read more »

Increased daily physical activity reduces the risk of Alzheimer’s disease and cognitive decline

Increased daily physical activity is associated with a reduction in the risk of Alzheimer’s disease (AD), found a recent cohort study published in the journal Neurology. “Physical activity can be easily done by all elderly or people at risk of AD. It is inexpensive and does not lead to any...  Read more »

Thrombolysis may be beneficial later and in older patients suffering an acute stroke

About 1.44 to 1.64 million cases of new stroke occur each year in India, with stroke sufferers losing over 6 million disability-adjusted life years (DALYs) annually due to death and disability, according to data from the World Health Organization (WHO). Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is used to...  Read more »

Even infrequent use of hypnotics may increase mortality risk

Taking hypnotic drugs, even sporadically, may increase the risk of death, a recent study has found. Researchers at the Scripps Clinic Sleep Center in La Jolla, California, United States, estimated the mortality risk of hypnotics in 10,529 adults who received hypnotic prescriptions and 23,676 matched controls; the subjects were followed...  Read more »

Retinopathy may be risk factor for cerebrovascular disease

In women aged 65 years and older, retinopathy is a marker for cerebrovascular disease that manifests as deficits in global cognition, a recent study found. Key Point: Retinopathy as a marker of small vessel disease is a risk factor for cerebrovascular disease in women aged 65 years and older. Proactive...  Read more »

Longstanding diabetes increases risk of stroke

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Strokes are much more likely in patients who have had diabetes for 10 or more years compared with those without diabetes, according to findings from the Northern Manhattan Study, a research study of stroke and stroke risk factors. “The findings emphasize the chronic nature of diabetes and the fact that...  Read more »

Forceps-assisted delivery associated with fewer neurologic complications

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Forceps-assisted vaginal deliveries appear to be associated with fewer total neurologic complications, including seizure, than either vacuum-assisted or Cesarean deliveries, a recent study found. However, forceps-assisted delivery, compared with the other delivery methods, was associated with a higher incidence of brachial plexus injury and facial nerve palsy. “Vacuum-assisted deliveries are...  Read more »
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