By: Dr. J. Gnanaraj and Dr. Bipin Kumar
INTRODUCTION
The Assam Rifles have their colonies in remote areas and they are self contained units where 1000 to 2000 people live together. One such colony is near a place called Jalukie in Nagaland. Recently within a week 17 children presented with ulcers in the mouth, foot and hands that prevented them from eating and some had fever at presentation. All of them were from one housing unit. During the initial week they were treated conservatively with Paracectamol syrup and intravenous fluids if they were not able to eat.
Later they were give Zinc syrup and it helped them start eating from the next day. To check if it was the zinc syrup that made the difference it was not used in few patients and they did take a much longer time. A proper controlled trial is necessary to see if the Zinc syrup significantly reduced the morbidity due to the Hand Foot Mouth disease. Zinc is an immune-modulator that has shown to improve the symptoms of some of the viral diseases [2].
DISCUSSION
It is caused by enterovirus [16 & 17] called Coxsackie virus [1]. It is transmitted through contact with patients or things that they touch. It generally starts as a sore throat and then the ulcers develop. It is a self limiting disease that goes away after 10 days. The virus can stay for a long time especially in the spit and in the stools.
Zinc has an important role as an immune-modulator and has been used successfully for treatment of viral dermatological conditions [2]. Those who were started on zinc syrup were able to start eating without significant pain within 48 hours while those who did not receive it had problems with eating even after four to five days.
References (click to show/hide)
- Available from: http://www.webmd.com/children/hand-foot-mouth-disease#1
- Al-Gurairi FT1, Al-Waiz M, Sharquie KE. Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial. Br J Dermatol 2002 Mar;146(3):423-31.
One Comment