
The striking genetic heterogeneity displayed by HBV result mostly from copy errors introduced by viral polymerase during replication of its DNA genome through reverse transcription of pregenomic RNA [1]. However, the long-term fate of these abundant genetic changes depend upon the interactions of HBV with its host, the dramatic intra-host diversification and on different genetic processes such as…
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Resistance Patterns among Multidrug-Resistant Tuberculosis Patients in Greater Metropolitan Mumbai
India has one of the highest burdens of multidrug-resistant tuberculosis (MDR-TB) globally, with an estimated 64,000 patients having MDR strains among notified pulmonary TB cases in 2013, which would account for more than 20 percent of the estimated global burden of drug-resistant tuberculosis [1]. The increase in MDR-TB cases within the country has…
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