Tag Archives: visceral leishmaniasis

Towards Elimination of Visceral Leishmaniasis in the Indian Subcontinent—Translating Research to Practice to Public Health

About 147 million people are at risk of visceral leishmaniasis, in the Southeast Asian region. The largely localized geographic endemicity, anthroponotic transmission with humans as the only host reservoir, the sandfly species Phlebotomous argentipes as the only vector species, and the…

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Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum

Depending on the geographical location, visceral leishmaniasis can either be caused by Leishmania donovani (East Africa and Indian subcontinent) or L. infantum (Mediterranean basin, central Asia and Latin America). Although both species are closely related and belong to the same complex (L. donovani complex), transmission of L. donovani is mostly anthroponotic while…

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Longitudinal Study of Transmission in Households with Visceral Leishmaniasis, Asymptomatic Infections and PKDL in Highly Endemic Villages in Bihar, India

Visceral leishmaniasis (VL), also known as kala-azar, is a neglected vector-borne disease caused by a protozoan parasite, Leishmania donovani and is transmitted by the…

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Longitudinal Study of Transmission in Households with Visceral Leishmaniasis, Asymptomatic Infections and PKDL in Highly Endemic Villages in Bihar, India

Visceral leishmaniasis, also known as kala-azar, is a neglected vector-borne disease caused by a protozoan parasite, Leishmania donovani and is transmitted by the bite of…

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Immunotherapeutic Potential of Eugenol Emulsion in Experimental Visceral Leishmaniasis

Leishmaniasis, a complex vector-borne parasitic syndrome, is caused by obligate intra-macrophagic protozoan parasites of the genus Leishmania, a member of the order Kinetoplastida…

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Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm

Visceral leishmaniasis caused by the species Leishmania donovani, is the most severe form of leishmaniasis and is endemic in the region of Indian subcontinent. Due to its digenic …

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Visceral Leishmaniasis on the Indian Subcontinent: Modelling the Dynamic Relationship between Vector Control Schemes and Vector Life Cycles

The deadliest form of leishmaniasis, visceral leishmaniasis, is vector-transmitted through the bite of phlebotomine sand flies in the Phlebotomus and Lutzomyia genera…

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