Tag Archives: tuberculosis

The Clinical Usefulness of Tuberculin Skin Test versus Interferon-Gamma Release Assays for Diagnosis of Latent Tuberculosis in HIV Patients

Co-infection of Human immunodeficiency virus (HIV) and tuberculosis (TB) is a major public health concern. Recent estimates indicated about 9 million new cases of TB annually worldwide, of which 1.1 million are people living with HIV…

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Household Contact Screening and Yield of Tuberculosis Cases – A Clinic Based Study in Chennai, South India

Contact screening is a key component in national tuberculosis (TB) programs and is an active case finding strategy to identify more TB cases. It involves systematic screening of the contacts of known TB patients…

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Mycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism

Two component systems permit bacteria to sense and adapt to diverse environmental stresses. The DevR-DevS TCS (also called DosR-DosS) is one of the best characterized TCS of Mycobacterium tuberculosis…

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Immunological Evidence for the Role of Mycobacteria in Sarcoidosis: A Meta-Analysis

Mycobacterium tuberculosis is the second most common infectious cause of death in adults worldwide (HIV is the most common). The human host serves as a natural reservoir for M. tuberculosis, which is an intracellular obligate and…

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A Systematic Review of the Prevalence and Pattern of Imaging Defined Post-TB Lung Disease

Pulmonary TB remains an important cause of chronic respiratory impairment in LMICs. 5.2 million incident cases of PTB were reported globally…

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The Effectiveness and Safety of Fluoroquinolone-Containing Regimen as a First-Line Treatment for Drug-Sensitive Pulmonary Tuberculosis

Pulmonary tuberculosis is a contagious disease in which the human lung is primarily infected by a pathogen, Mycobacterium tuberculosis

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Effects of Multidrug Resistant Tuberculosis Treatment on Patients’ Health Related Quality of Life

Health Related Quality of Life (HRQoL) is defined as “the extent to which patient’s subjective perception of physical, mental and social well being are affected on a day to day basis by a disease and its treatment(s)…

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