Tag Archives: tuberculosis

Prevalence and Associated Factors of Tuberculosis and Diabetes Mellitus Comorbidity: A Systematic Review

Diabetes mellitus and tuberculosis are major killers of mankind across the globe. The World Health Organization global report for 2015 indicates that, there were 10.4 million new cases and 1.4 million deaths resulting from…

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Field Evaluation of a Blood Based Test for Active Tuberculosis in Endemic Settings

Mycobacterium tuberculosis (M. tb.), the etiologic agent of tuberculosis, is one of the most successful human pathogens on the planet. Approximately two billion people are infected with M. tb. worldwide…

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The impact of Glycemic Status on Radiological Manifestations of Pulmonary Tuberculosis in Diabetic Patients

Tuberculosis (TB) and diabetes mellitus (DM) are both important global health issues. In addition, the link between TB and DM has been demonstrated, and these conditions may complicate each other at…

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Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients

The success of Mycobacterium tuberculosis as a human pathogen is largely due to its ability to switch between latent and active states and to adapt to different environments and stresses. These adaptations are reflected by…

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Comparison of TST and IGRA in Diagnosis of Latent Tuberculosis Infection in a High TB-Burden Setting

According to the World Health Organization Global TB report, 2015 approximately one- third of the world population is infected with Mycobacterium tuberculosis. Although individuals with LTBI are asymptomatic, however, they constitute an important…

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Priority-Setting for Novel Drug Regimens to Treat Tuberculosis: An Epidemiologic Model

The number of available or prospective drugs for treating tuberculosis (TB) is undergoing a long-overdue expansion. Delamanid and bedaquiline, both recently approved for the treatment of multidrug-resistant TB, are the first novel agents registered for TB treatment in…

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Prevalence of Latent Tuberculosis among Health Care Workers in High Burden Countries: A Systematic Review and Meta-Analysis

Health care workers (HCWs) are at increased risk of acquiring tuberculosis (TB) than the general population. The risk of TB in HCWs is of particular importance in the 22 high TB burden mostly low- and middle-income countries that…

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