Tag Archives: tuberculosis

Diagnostic Utility of a Line Probe Assay for Multidrug Resistant-TB in Smear-Negative Pulmonary Tuberculosis

Pulmonary tuberculosis is a major public health disease that ranks as the second-most leading cause of death worldwide, after human immunodeficiency virus infection. In 2016, there were 10.4 million new…

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Comorbidities in Pulmonary Tuberculosis Cases in Puducherry and Tamil Nadu, India: Opportunities for Intervention

An estimated 10.6 million cases of tuberculosis (TB) occur annually in the world, and India accounts for 27% of these. The emergence of drug-resistant TB creates a renewed sense of urgency to control…

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Prevalence and Associated Factors of Tuberculosis and Diabetes Mellitus Comorbidity: A Systematic Review

Diabetes mellitus and tuberculosis are major killers of mankind across the globe. The World Health Organization global report for 2015 indicates that, there were 10.4 million new cases and 1.4 million deaths resulting from…

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Field Evaluation of a Blood Based Test for Active Tuberculosis in Endemic Settings

Mycobacterium tuberculosis (M. tb.), the etiologic agent of tuberculosis, is one of the most successful human pathogens on the planet. Approximately two billion people are infected with M. tb. worldwide…

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The impact of Glycemic Status on Radiological Manifestations of Pulmonary Tuberculosis in Diabetic Patients

Tuberculosis (TB) and diabetes mellitus (DM) are both important global health issues. In addition, the link between TB and DM has been demonstrated, and these conditions may complicate each other at…

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Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients

The success of Mycobacterium tuberculosis as a human pathogen is largely due to its ability to switch between latent and active states and to adapt to different environments and stresses. These adaptations are reflected by…

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Comparison of TST and IGRA in Diagnosis of Latent Tuberculosis Infection in a High TB-Burden Setting

According to the World Health Organization Global TB report, 2015 approximately one- third of the world population is infected with Mycobacterium tuberculosis. Although individuals with LTBI are asymptomatic, however, they constitute an important…

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