Tag Archives: TB

Identifying factors that predict meningeal tuberculosis could improve outcomes

Among the various forms of tuberculosis (TB) affecting the central nervous system, meningeal TB is the most severe and has the highest mortality rate. A retrospective study conducted in South India focused on identifying factors that predict mortality to assist clinicians in treating these patients and formulating prognoses for them…. 

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Delamanid may be beneficial as an add-on therapy to the standard treatment regimen of multidrug resistant tuberculosis

The investigational antibiotic delamanid increased 2-month sputum-culture conversion in patients with multidrug-resistant pulmonary tuberculosis (TB). This was the main finding of a recent randomized, placebo-controlled trial that sought to determine the efficacy and safety of delamanid added to standard therapy vs standard therapy alone in this population. Key Point: Delamanid,… 

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Pediatric multidrug-resistant tuberculosis gets more attention

Due to difficulties in establishing accurate diagnoses and lower priorities assigned by tuberculosis (TB) control programs, pediatric TB has been relatively neglected. Treatment delays lead to the progression of disease, increased risk of infectiousness, greater complications, and higher rates of morbidity and death. “The key learnings identified from this study… 

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Posted in Infectious Disease, Pediatrics, Pharmacology, Primary Care | Also tagged , , , , , , , , , , | Volume: | Leave a comment

Treat tuberculosis with triple therapy, using the correct dose and duration to prevent resistant organisms

More than 400,000 people die of tuberculosis (TB) in India every year. Drug-resistant TB is due to inappropriate drug and dose prescribing, and/or lack of patient medication adherence. Careless management has led to the emergence of progressively more resistant TB to anti-TB medications. “Drug-resistant tuberculosis, the dreaded form of the… 

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Treat tuberculosis in pregnancy using first-line agents, but wait for second-line agents

Beware of false-positive skin tests in pregnant women vaccinated with BCG (Bacille Calmette Guerin vaccine for tuberculosis [TB]), in those previously treated for TB infection, or in those previously infected with other Mycobacterium species. False negatives can occur in those with compromised immune systems (eg, HIV) or due to technical… 

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Posted in Infectious Disease, Ob/Gyn, Pharmacology | Also tagged , , , , , , , , , , , , , , , , , , , | Volume: | 1 Response