Tag Archives: rotavirus

Estimating the Incidence of Rotavirus Infection in Children from India and Malawi from Serial Anti-Rotavirus IgA Titres

Prior to wide-spread rotavirus vaccination, rotavirus was responsible for over 450 000 deaths in young children…

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Health Impact and Cost-Effectiveness of a Domestically-Produced Rotavirus Vaccine in India: A Model Based Analysis

Each year, rotavirus gastroenteritis claims the lives of an estimated 215,000 children under five years of age; 22% of these deaths are estimated to…

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Evaluating the Impact of Breastfeeding on Rotavirus Antigenemia and Disease Severity in Indian Children

Rotavirus is the major worldwide cause of acute gastroenteritis with severe dehydrating diarrhea in children below 5 years. WHO estimates that RV is responsible for 40% of AGE amongst children…

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Community Based Case-Control Study of Rotavirus Gastroenteritis among Young Children during 2008-2010 Reveals Vast Genetic Diversity and Increased Prevalence of G9 Strains in Kolkata

Severe gastroenteritis in children below 5 years of age is a major public health problem in humans globally [1]. Worldwide approximately 10.6 million children die before their fifth birthday of which 20% deaths are attributed to diarrhoeal diseases [2]. Although large number of bacterial, viral and parasitic pathogens have been implicated to cause diarrhoea, but…

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An update on the current and future management of rotavirus in India

More than 110 million children in India aged younger than 5 years have diarrhea, with an average of 3.2 episodes a year. It’s estimated that 7% to 8% of community-based episodes are due to rotavirus—a total of 25 million to 28 million episodes in young children a year, according to… 

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Could a rotavirus vaccine based on genotypes prevalent in India be on the horizon?

Rotavirus is a leading cause of severe infant diarrhea, causing an estimated 100,000 deaths each year in India, according to the World Health Organization. While most young children in the world contract rotavirus at some point in their early childhood, the disease course is usually much more severe for children… 

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No increase in intussusception after RotaTeq immunization

Infants given RotaTeq, a rotavirus vaccine, had no increased risk of intussusception after immunization compared with infants not given RotaTeq, according to the 4-year Vaccine Safety Datalink (VSD) study. The multiple-site study, conducted in the United States and published earlier this year in the Journal of the American Medical Association,… 

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