Tag Archives: rifampin

Delamanid may be beneficial as an add-on therapy to the standard treatment regimen of multidrug resistant tuberculosis

The investigational antibiotic delamanid increased 2-month sputum-culture conversion in patients with multidrug-resistant pulmonary tuberculosis (TB). This was the main finding of a recent randomized, placebo-controlled trial that sought to determine the efficacy and safety of delamanid added to standard therapy vs standard therapy alone in this population. Key Point: Delamanid,… 

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Treat tuberculosis with triple therapy, using the correct dose and duration to prevent resistant organisms

More than 400,000 people die of tuberculosis (TB) in India every year. Drug-resistant TB is due to inappropriate drug and dose prescribing, and/or lack of patient medication adherence. Careless management has led to the emergence of progressively more resistant TB to anti-TB medications. “Drug-resistant tuberculosis, the dreaded form of the… 

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Treat tuberculosis in pregnancy using first-line agents, but wait for second-line agents

Beware of false-positive skin tests in pregnant women vaccinated with BCG (Bacille Calmette Guerin vaccine for tuberculosis [TB]), in those previously treated for TB infection, or in those previously infected with other Mycobacterium species. False negatives can occur in those with compromised immune systems (eg, HIV) or due to technical… 

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Posted in Infectious Disease, Ob/Gyn, Pharmacology | Also tagged , , , , , , , , , , , , , , , , , , , | Volume: | 1 Response