Tag Archives: plasmodium falciparum

Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays

The burden of malaria in India has halved over the last 15 years, yet India continues to account for over 70% of malaria cases in South East Asia. The ‘National Framework for Malaria Elimination in India 2016–2030’ has two aims: eliminating malaria throughout the country by…

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Population Density, Climate Variables and Poverty Synergistically Structure Spatial Risk in Urban Malaria in India

The pronounced and on-going increase in urban population, combined with climate change and economic disparities could act synergistically on the transmission dynamics of malaria…

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Prevalence of pfhrp2 and/or pfhrp3 Gene Deletion in Plasmodium falciparum Population in Eight Highly Endemic States in India

Malaria prevalence in India varies between states and eight out of 35 states and union territories are contributing to 80% of total malaria cases, 85% Plasmodium falciparum, and 70% of deaths due to malaria in the country…

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Erythropoietin Levels Increase during Cerebral Malaria and Correlate with Heme, Interleukin-10 and Tumor Necrosis Factor-Alpha in India

Malaria eradication is a worldwide public health priority. Despite tremendous efforts, children and adults still die from this plague every year due to severe disease manifestations. Cerebral malaria is the deadliest complication…

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Climate Drivers on Malaria Transmission in Arunachal Pradesh, India

Malaria is a major health problem predominantly in tropical and subtropical countries [1]. According to World Health Organisation (WHO), there are about 219 million cases of malaria of which 660,000 deaths were recorded worldwide in 2010. In South East Asian region, 76% of the total malaria cases reported were mainly contributed by India (24 million cases per year), followed by Indonesia, and Myanmar [2]. North-eastern states of India are known for malarial endemicity that accounts for…

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Correlation of Molecular Markers, Pfmdr1-N86Y and Pfcrt-K76T, with In Vitro Chloroquine Resistant Plasmodium falciparum

Malaria is one of the major public health problems of the malaria affected countries, including India. In India, around 1.5 million laboratory confirmed cases of malaria are reported annually, out of which 50% cases are due to Plasmodium falciparum alone. Chloroquine (CQ) has been the most effective drug in the treatment of non-complicated malaria.

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Clinical Features and Outcome in Children with Severe Plasmodium falciparum Malaria: A Meta-Analysis

Although most of the 500 million clinical cases of malaria due Plasmodium falciparum estimated to occur globally are uncomplicated [1], some (1–4%) are considered severe enough to require hospitalization and/or parenteral antimalarial treatment [2]. In children, the term ‘severe malaria’ is currently applied…

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