Tag Archives: pharmacotherapy

Visceral leishmaniasis (kala-azar) diagnosis and treatment in India

Visceral leishmaniasis, or kala-azar (KA), is a tropical disease spread by the bite of a sand fly that carries the parasite Leishmania donovani. Kala-azar is endemic in India where the incidence of new cases is about 147,000–283,000 annually. Treatment duration is long and available drugs are toxic, requiring monitoring and… 

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Posted in Infectious Disease | Also tagged , , , , | Volume: | Leave a comment

Vasopressin investigated as potential rescue therapy in critically ill children

Vasopressin, a synthesized peptide hormone, is emerging as a potentially major advancement in the management of critically ill children. If future and ongoing clinical trials support its efficacy and safety in the pediatric population, vasopressin could be used as rescue therapy in children with refractory shock and cardiac arrest, with… 

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Posted in Pediatrics, Pharmacotherapy, Primary Care | Also tagged , , , , , , , , , , , , | Volume: | Leave a comment

Routine use of antibiotics not warranted in most cases of rhinosinusitis

Antibiotic treatment is no better than placebo at improving symptoms in patients with acute uncomplicated rhinosinusitis, according to a study recently published in the Journal of the American Medical Association (JAMA). Key Point: Routine antibiotics for acute rhinosinusitis do not improve symptoms and are not warranted. Watchful waiting is a… 

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Posted in Allergy and Immunology, Pharmacology, Primary Care | Also tagged , , , , , , , | Volume: | Leave a comment

Not all oral type 2 diabetes medications are created equally; advice for starting monotherapy

While all of the oral medications approved to treat type 2 diabetes mellitus (T2DM) effectively lower blood glucose, each medication’s effects on other clinical events vary. The costs of these drugs also vary. A recent study of 254,973 T2DM patients who were newly initiated on oral hypoglycemic monotherapy examined prescribing… 

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Posted in Diabetes, Endocrinology, Non-Communicable Disease, Pharmacology, Primary Care | Also tagged , , , , , , , , , , , | Volume: | Leave a comment

Daily aspirin use ups the risk of wet aging macula disorder

Frequent aspirin use may promote wet aging macula disorder (AMD), which is also referred to as age-related macular degeneration, according to results from a population-based study in 7 European countries. The effect of aspirin use on AMD prevalence is controversial, as studies of the association between aspirin use and AMD… 

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Posted in Ophthalmology, Pharmacology, Primary Care | Also tagged , , , | Volume: | Leave a comment

Non-sedating antihistamines recommended to treat urticaria

Most doctors know how complex the management of urticaria— particularly chronic urticaria—can be. New clinical guidelines will help you identify and treat your patients with this condition. Specifically, the Consensus Statement, published recently in the Indian Journal for Dermatology, provides helpful information on pharmacotherapeutic management of urticaria. “This Consensus Statement… 

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Posted in Dermatology, Primary Care | Also tagged , , , , , , | Volume: | Leave a comment