Vasopressin, a synthesized peptide hormone, is emerging as a potentially major advancement in the management of critically ill children. If future and ongoing clinical trials support its efficacy and safety in the pediatric population, vasopressin could be used as rescue therapy in children with refractory shock and cardiac arrest, with…
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Antibiotic treatment is no better than placebo at improving symptoms in patients with acute uncomplicated rhinosinusitis, according to a study recently published in the Journal of the American Medical Association (JAMA). Key Point: Routine antibiotics for acute rhinosinusitis do not improve symptoms and are not warranted. Watchful waiting is a…
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While all of the oral medications approved to treat type 2 diabetes mellitus (T2DM) effectively lower blood glucose, each medication’s effects on other clinical events vary. The costs of these drugs also vary. A recent study of 254,973 T2DM patients who were newly initiated on oral hypoglycemic monotherapy examined prescribing…
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Frequent aspirin use may promote wet aging macula disorder (AMD), which is also referred to as age-related macular degeneration, according to results from a population-based study in 7 European countries. The effect of aspirin use on AMD prevalence is controversial, as studies of the association between aspirin use and AMD…
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Most doctors know how complex the management of urticaria— particularly chronic urticaria—can be. New clinical guidelines will help you identify and treat your patients with this condition. Specifically, the Consensus Statement, published recently in the Indian Journal for Dermatology, provides helpful information on pharmacotherapeutic management of urticaria. “This Consensus Statement…
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Visceral leishmaniasis (kala-azar) diagnosis and treatment in India
Visceral leishmaniasis, or kala-azar (KA), is a tropical disease spread by the bite of a sand fly that carries the parasite Leishmania donovani. Kala-azar is endemic in India where the incidence of new cases is about 147,000–283,000 annually. Treatment duration is long and available drugs are toxic, requiring monitoring and…
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