Tag Archives: multidrug-resistant tuberculosis

MDR-TB Treatment as Prevention: The Projected Population-Level Impact of Expanded Treatment for Multidrug-Resistant Tuberculosis

Multidrug resistant tuberculosis (MDR-TB) poses one of the greatest threats to TB control worldwide. Not only is the incidence of MDR-TB rising in many areas, curtailing…

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Effects of Multidrug Resistant Tuberculosis Treatment on Patients’ Health Related Quality of Life

Health Related Quality of Life (HRQoL) is defined as “the extent to which patient’s subjective perception of physical, mental and social well being are affected on a day to day basis by a disease and its treatment(s)…

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Disease Control Implications of India’s Changing Multi-Drug Resistant Tuberculosis Epidemic

Multi-drug resistant tuberculosis (MDR TB) is a major health challenge in India that is gaining increasing public attention, but the implications of India’s evolving MDR TB epidemic are poorly understood.

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Delamanid may be beneficial as an add-on therapy to the standard treatment regimen of multidrug resistant tuberculosis

The investigational antibiotic delamanid increased 2-month sputum-culture conversion in patients with multidrug-resistant pulmonary tuberculosis (TB). This was the main finding of a recent randomized, placebo-controlled trial that sought to determine the efficacy and safety of delamanid added to standard therapy vs standard therapy alone in this population. Key Point: Delamanid,… 

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Pediatric multidrug-resistant tuberculosis gets more attention

Due to difficulties in establishing accurate diagnoses and lower priorities assigned by tuberculosis (TB) control programs, pediatric TB has been relatively neglected. Treatment delays lead to the progression of disease, increased risk of infectiousness, greater complications, and higher rates of morbidity and death. “The key learnings identified from this study… 

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