High levels of 17β-estradiol in the plasma of postmenopausal women were associated with an increased risk of ischemic arterial disease, according to a recent prospective cohort study. High estradiol levels are known to correlate with cardiovascular risk factors such as obesity, abnormal blood lipids, and diabetes. According to the Indian…
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mdCurrent Conference Report: Digestive Disease Week Hormone replacement therapy (HRT) may increase the risk of ulcerative colitis in postmenopausal women, according to a new study presented at Digestive Disease Week 2012. “It is important that clinicians are aware of the results of this study, but it should not lead to…
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Estrogen alone after a hysterectomy reduces the risk of invasive breast cancer, according to a follow-up analysis of postmenopausal women enrolled in the U.S. Women’s Health Initiative (WHI) study. In the WHI study, women aged 50 to 79 years who had undergone hysterectomy were randomized to receive estrogen alone (0.625…
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Menopausal hormone replacement therapy reduces fractures but increases risks for other conditions
A great deal of controversy surrounds the use of menopausal hormone replacement therapy (HRT) for the prevention of chronic conditions. “There are robust data now coming in that there is a window of opportunity in the early menopausal years when HRT may reduce the risk of cardiovascular disease. It would…
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