Tag Archives: HIV

Sub-Therapeutic Nevirapine Concentration During Antiretroviral Treatment Initiation Among Children Living with HIV: Implications for Therapeutic Drug Monitoring

Nevirapine was the first non-nucleoside reverse transcriptase inhibitor approved by the FDA for pediatric use since 1998. Although nevirapine has a low genetic barrier to…

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Gender Differences in Factors Related to HIV Risk Behaviors among People Who Inject Drugs in North-East India

Injection drug use is an important driver of HIV epidemics in different regions of the world including India, which is home to 168,000–1.1 million people who inject drugs with a high prevalence of HIV and…

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Development, Validation, and Field-Testing of an Instrument for Clinical Assessment of HIV-Associated Neuropathy and Neuropathic Pain in Resource-Restricted and Large Population Study Settings

HIV-associated sensory peripheral neuropathy (HIV-SN) is a length-dependent distal symmetrical polyneuropathy that occurs in individuals with treated and untreated HIV infection…

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The Clinical Usefulness of Tuberculin Skin Test versus Interferon-Gamma Release Assays for Diagnosis of Latent Tuberculosis in HIV Patients

Co-infection of Human immunodeficiency virus (HIV) and tuberculosis (TB) is a major public health concern. Recent estimates indicated about 9 million new cases of TB annually worldwide, of which 1.1 million are people living with HIV…

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Is There a Need for Viral Load Testing to Assess Treatment Failure in HIV-Infected Patients Who Are about to Change to Tenofovir-Based First-Line Antiretroviral Therapy?

Both the 2010 and 2013 WHO Guidelines on the use of antiretroviral drugs for treating and preventing HIV infection have emphasized a) the phasing out of stavudine (d4T) and replacement with tenofovir…

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A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort

HCV co-infection is recognized as a major cause of morbidity and mortality among HIV-1 infected patients. HIV-1 co-infection is associated with increased HCV load and accelerated rates of liver disease progression…

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An Estimation of Mortality Risks among People Living with HIV in Karnataka State, India

Globally, it is estimated that 35.3 million [32.2 million–38.8 million] people were living with HIV (PLHIV) by the year 2012. At the same time while about 1.5 million people die from HIV/AIDS-related causes, about 2.1 million new cases of HIV were detected…

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