Approximately 2 million of a total of 12.7 million new cancer cases worldwide are directly attributable to infectious disease, a recently published study found. Multiple infectious diseases, such as Helicobacter pylori, human papillomavirus (HPV), Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human herpes T-cell lymphotropic virus…
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Even high-dose antiherpetic therapy may not be enough to quell short bursts of subclinical genital herpes simplex virus (HSV) reactivation, which may account for the continued transmission of HSV despite suppressive antiviral therapy. Researchers from the University of Washington, Seattle, United States, conducted 3 separate but complementary open-label crossover studies…
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Herpesvirus-associated central nervous system diseases after allogeneic hematopoietic stem cell transplantation
Herpesviruses, the family of neurotropic viruses, may cause encephalitis/myelitis of various degrees of severity in immunocompetent individuals [1,2]. Epidemiological studies demonstrate that α-herpesviruses, such as herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV), are the most frequent etiological agents found in sporadic viral encephalitis/myelitis [2,3]. β- and γ-herpesviruses, such as cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human herpes virus 6-8 (HHV6-8), are known to cause encephalitis/myelitis, but it is rare in immunocompetent individuals [3,4].
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