Tag Archives: hepatitis B

Occult Hepatitis B Virus Infection in HIV Positive Patients at a Tertiary Healthcare Unit in Eastern India

Hepatitis B virus (HBV) infection continues to be a global health concern despite the presence of an effective vaccine. Worldwide, approximately 2 billion people have been infected with HBV at some stage of life, of them…

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Virological Characteristics of Acute Hepatitis B in Eastern India

Hepatitis B virus (HBV) is a global health threat affecting about 350 million people across the world. HBV leads to a wide spectrum of clinical presentations ranging from acute…

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A Rare HBV Subgenotype D4 with Unique Genomic Signatures Identified in North-Eastern India

The striking genetic heterogeneity displayed by HBV result mostly from copy errors introduced by viral polymerase during replication of its DNA genome through reverse transcription of pregenomic RNA [1]. However, the long-term fate of these abundant genetic changes depend upon the interactions of HBV with its host, the dramatic intra-host diversification and on different genetic processes such as…

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Mutation Profiling of the Hepatitis B Virus Strains Circulating in North Indian Population

Hepatitis B virus (HBV) is the most common cause of chronic hepatitis, Cirrhosis and Hepatocellular Carcinoma (HCC) globally [1], [2]. HBV is a DNA Virus with 3200 nucleotides and has four Open Reading Frames (ORFs) encoding for hepatitis B surface or envelope proteins, core peptide, X peptide and DNA-polymerase enzyme. It replicates through…

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Molecular Characterization of HBV Strains Circulating among the Treatment-Naive HIV/HBV Co-Infected Patients of Eastern India

Hepatitis B virus (HBV) infection remains a global health problem in spite of an effective vaccine, with approximately 400 million people being chronically infected with HBV worldwide [1]. HBV, the archetype member of the Hepadnaviridae family, is a partially double stranded DNA virus of approximately…

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Significant number of global cancer cases attributed to infectious diseases

Approximately 2 million of a total of 12.7 million new cancer cases worldwide are directly attributable to infectious disease, a recently published study found. Multiple infectious diseases, such as Helicobacter pylori, human papillomavirus (HPV), Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human herpes T-cell lymphotropic virus… 

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