Tag Archives: diarrhea

Oral cholera vaccine Shanchol is a low-cost option in India

Download the free patient handout PDF near the end of this article! Shanchol, an Oral Cholera Vaccine (OCV) that is devoid of subunit B, was recently licensed in India in 2009 and WHO-prequalified in 2011. Shanchol, India’s first OCV, is produced by Shantha Biotechnics, and as of May 2012, it… 

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An update on the current and future management of rotavirus in India

More than 110 million children in India aged younger than 5 years have diarrhea, with an average of 3.2 episodes a year. It’s estimated that 7% to 8% of community-based episodes are due to rotavirus—a total of 25 million to 28 million episodes in young children a year, according to… 

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Could a rotavirus vaccine based on genotypes prevalent in India be on the horizon?

Rotavirus is a leading cause of severe infant diarrhea, causing an estimated 100,000 deaths each year in India, according to the World Health Organization. While most young children in the world contract rotavirus at some point in their early childhood, the disease course is usually much more severe for children… 

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How physicians can help with efforts to decrease child mortality in India

The United Nation’s Millennium Development Goal 4 (MDG4) calls for a reduction in childhood mortality by two-thirds between 1990 and 2015. A recent paper from the World Health Organization (WHO) and UNICEF’s Child Health Epidemiology Reference Group tracks worldwide progress in childhood mortality. The investigators found that the number of… 

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Macrolide antibacterial agent fidaxomicin may be an alternative to vancomycin for Clostridium difficile-associated diarrhea

Fidaxomicin, a macrolide antibiotic, is noninferior to vancomycin in the treatment of Clostridium difficile diarrhea in terms of clinical cure. This was the main finding of a recent randomized trial that sought to demonstrate the noninferiority of fidaxomicin for this indication. C difficile, which causes 15% to 25% of antibiotic-associated… 

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Posted in Gastroenterology, Infectious Disease, Pharmacology, Primary Care | Also tagged , , , , , , , | Volume: | Leave a comment

Proton-pump inhibitors may be linked to increased risk of C. difficile-associated diarrhea

Proton-pump inhibitors (PPIs) may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD). Doctors and patients are being warned that if a patient develops diarrhea that does not improve while receiving a PPI, then CDAD should be considered as a diagnosis and managed appropriately, according to an advisory… 

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Study identifies risk factors for prolonged diarrheal duration, complications in children

A new pediatric study has found that younger age, malnourishment, dehydration, fever, dysentery (bloody stool), longer duration of diarrhea prior to admission, and the failure to treat diarrhea with medication put children suffering an acute bout of diarrhea at increased odds of experiencing a prolonged course or complication. Key Point:… 

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