Tag Archives: cholera

Identification of Burden Hotspots and Risk Factors for Cholera in India: An Observational Study

Cholera has existed in India for centuries, and is an important public health problem in several parts of the country.. Based on a ten year review from 1997 to 2006, 21 states reported cholera and 12 had multiple outbreaks. During the 10-year period studied, the states having the highest number of…

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Cholera Forecast for Dhaka, Bangladesh, with the 2015-2016 El Niño: Lessons Learned

Climate variability, specifically the El Niño-Southern Oscillation, has been shown to influence the year-to-year variation of seasonal outbreaks of cholera in Bangladesh. In particular, interannual variations of the disease have been shown to be positively associated with…

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Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process

Cholera is the most severe of all infectious diarrheal diseases, which if not adequately treated can have a high mortality up to 50%…

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Potential for Controlling Cholera Using a Ring Vaccination Strategy

The current prequalified oral cholera vaccines provide over 80% (direct) protection in the first 6 mo after vaccination, with protection of up to 65% for 5 y estimated in an endemic settin. However, this estimate does not include herd protection…

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Micro-scale Spatial Clustering of Cholera Risk Factors in Urban Bangladesh

Cholera is responsible for over 100,000 deaths each year and is endemic in many countries. In Bangladesh, approximately 450,000 cases of cholera are estimated each year. Cholera cases have been known to…

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Cholera in Pregnancy: A Systematic Review and Meta-Analysis of Fetal, Neonatal, and Maternal Mortality

Cholera is an acute diarrheal disease caused by the bacterium Vibrio cholerae and transmitted through fecally-contaminated water or food, which affects children and adults. Around 20% of the infected individuals develop…

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Flexibility of Oral Cholera Vaccine Dosing—A Randomized Controlled Trial Measuring Immune Responses Following Alternative Vaccination Schedules in a Cholera Hyper-Endemic Zone

As a disease of poverty and inequity, cholera is often prevalent in areas of compromised sanitation, overcrowded conditions, and poor quality of water supply. An increasing number of longer lasting outbreaks have dramatically impacted the least developed countries (LDCs), including those in Africa, South Asia, and the Hispaniola island region. Living conditions in LDC populations often favor…

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