Tag Archives: cardiovascular risk

Use of non-steroidal anti-inflammatory drugs that elevate cardiovascular risk

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used of therapeutic agents. Taken singly or in combination with other classes of drug, they relieve symptoms across multiple clinical indications, including short and long term pain states and a range of musculoskeletal disorders.

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Cardiovascular risk of NSAIDs: Time to translate knowledge into practice

Clinical use of non-steroidal anti-inflammatory drugs (NSAIDs) carries cardiovascular risk, which acquires implications for public health against the backdrop of rising chronic disease rates in low- and middle-income countries (LMICs). New evidence from an international study conducted by Patricia McGettigan and David Henry and published this week in PLOS Medicine [1] sheds light on how emerging evidence about NSAID risk is poorly translated into practice and sales in countries around the world, raising questions about the use and promotion of potentially harmful drugs…

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Omega-3 fatty acid supplements do not lower risk of major cardiovascular outcomes

Various clinical guidelines and government bodies recommend supplementation with omega-3 fatty acid supplements for cardiovascular-related indications ranging from triglyceride lowering to cardiovascular risk modification to preventive treatment following myocardial infarction. However, despite popular belief and practice, a recently published systematic review and meta-analysis found that supplementation with omega-3 polyunsaturated fatty… 

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Insulin has neutral effect on cardiovascular disease, cancer when used early in type 2 diabetes

mdCurrent Conference Report: 72nd Annual Scientific Sessions of the American Diabetes Association Basal insulin in patients with prediabetes or newly diagnosed type 2 diabetes has no effect on cardiovascular disease events over a median follow-up of 6.2 years, according to a recent study. An estimated 62 million people nationwide are… 

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Interventions can reverse clustering of hypertension and other cardiovascular risk factors

The Indian population is particularly susceptible to cardiovascular (CV) risk factors such as visceral adiposity and insulin resistance. However, few large studies have examined CV risk factors in the Indian population. An understanding the clustering of risk factors can provide vital clues for prevention and treatment. In a recent cross-sectional… 

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Blunted morning BP surge may increase risk of cardiovascular events in hypertensive patients

Due to the increased morning incidence of cardiovascular (CV) events, researchers have hypothesized that surges in blood pressure (BP) in the early morning hours may raise the risk of CV events such as myocardial infarction (MI), stroke, and sudden cardiac death. “This study adds to the growing body of information… 

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Economic development, healthcare infrastructure influence hyperlipidemia risk in patients with cardiovascular disease

A recent cohort study published in Circulation found that indices of economic development and health-system performance in different countries were found to significantly impact the odds of elevated total cholesterol in patients with hyperlipidemia and a history of cardiovascular disease. Prevalence of coronary heart disease is on the rise in… 

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