Menopausal hormone replacement therapy reduces fractures but increases risks for other conditions

A great deal of controversy surrounds the use of menopausal hormone replacement therapy (HRT) for the prevention of chronic conditions.

“There are robust data now coming in that there is a window of opportunity in the early menopausal years when HRT may reduce the risk of cardiovascular disease. It would be prudent for clinicians to evaluate data as it becomes available and counsel women based on current evidence.”
-Jyothi Unni, MD, president-elect (2013) of the Indian Menopause Society and head of Obstetrics and Gynecology at Jehangir Hospital, Pune, India

Following initial publication of results from the Women’s Health Initiative (WHI) in 2002, the U.S. Preventative Services Task Force recommended against the use of HRT for preventing chronic conditions.

A newly published systematic review in the Annals of Internal Medicine provides updated evidence concerning...

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