Identifying factors that predict meningeal tuberculosis could improve outcomes

Among the various forms of tuberculosis (TB) affecting the central nervous system, meningeal TB is the most severe and has the highest mortality rate. A retrospective study conducted in South India focused on identifying factors that predict mortality to assist clinicians in treating these patients and formulating prognoses for them.


“Since the ‘gold standard’ of positive bacteriologic culture has low sensitivity and molecular diagnostic tests such as the PCR [polymerase chain reaction assay] are not routinely available, using criteria are helpful in improving patient care and outcomes.”
-Jyotsna M. Joshi, MD, professor and head, Department of Pulmonary Medicine, TN Medical College, BYL Nair Hospital, Mumbai, India


Prior to this study, data were limited regarding predictors of mortality in patients diagnosed with meningeal TB. Diagnosing meningeal TB early is critical to its...

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