Antibiotics for treating acute ischemic stroke—a novel idea?

Minocycline 200 mg once daily taken at the time of first stroke symptoms may aid in improving clinical deficits following an acute ischemic stroke (AIS), but more robust and better controlled clinical studies are needed before the antibiotic can be recommended for this indication.

“There is an urgent need to evaluate newer treatment modalities for acute ischemic stroke that aren’t time-bound.”
-Sudhir Kumar, MD, DM, senior consultant neurologist, Apollo Health City, Jubilee Hills, Hyderabad, India, and member of mdCurrent-India’s Editorial Advisory Board

In India, stroke is a severely neglected condition and 1 of the 3 leading causes of disability and mortality, the other 2 being heart attack and cancer. At least 1.44 million to 1.64 million new cases of stroke occur every year, accounting for at least 6.4 million Disability Adjusted Life Years (DALYs). In addition, less than...

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This entry was posted in Neurology, Neurology Featured 2, Primary Care and tagged , , , , , , , , , , , , , , , . Volume: .


  1. Mahamood S Basharuthulla
    Posted Nov 2012 at 7:57 am | Permalink

    What is the mechanism by which antibiotics are working?
    If infection is suspected, what organism are responsible and proof of infection, ie culture, source method etc may kindly be explained
    M.S Basharuthulla; MD;FACP;FRCP’;FRCP-I;

  2. Manoj Malkan
    Posted Nov 2012 at 2:10 pm | Permalink

    No harm in trying. The way antibiotics are used in India, 5 days of Minocycline should no harm to anybody

  3. mahesh kumar goyal
    Posted Aug 2013 at 2:58 pm | Permalink

    both the grs behaved the same. role of minocycline?

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