Aspirin worth a look for preventing cervical cancer in HIV-infected women

Aspirin and other drugs that inhibit the synthesis of prostaglandin E2 (PGE2) should be evaluated for their potential to prevent cervical cancer in women infected with the human immunodeficiency virus (HIV), say researchers at Weill Cornell Medical College, New York City, United States. They found that HIV influences the production of PGE2, a promoter of inflammation and tumor development.

Aspirin blocks cyclo-oxygenase (COX)-2, an important chemical in the production of prostaglandins. Prostaglandin E2 has been linked to carcinogenesis in several tumor types, including cervical cancer.

According to a 2010 report by the WHO/ICO Information Centre on HPV and Cervical Cancer (http://apps.who.int/hpvcentre/statistics/dynamic/ico/country_pdf/IND.pdf), 134,420 women in India are diagnosed with cervical cancer annually, of whom 72,825 die from the disease. Cervical cancer ranks as the most frequent...

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This entry was posted in Infectious Disease, Ob/Gyn, Oncology, Pharmacology, Women's Health and tagged , , , , , , , , , . Volume: .

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