Infectious Disease Articles

Comparison of Monocyte Gene Expression Among Patients with Neurocysticercosis-Associated Epilepsy, Idiopathic Epilepsy and Idiopathic Headaches in India

Neurocysticercosis (NCC) is a brain infection by Taenia solium larvae which is a common cause of acquired epilepsy. NCC may consist of single or multiple larvae (cysts) that progress from viable vesicular to colloidal and granuloma states and finally... Read more »

Post-Dengue Acute Disseminated Encephalomyelitis: A Case Report and Meta-Analysis

Dengue, a worldwide prevalent mosquito-borne infectious disease, is a flavivirus spread by several species of Aedes type mosquitos, mainly Aedes aegypti. Dengue has become a dangerous burden and is widely spread in more than... Read more »

Candida Auris: A Rapidly Emerging Cause of Hospital-Acquired Multidrug-Resistant Fungal Infections Globally

Candidiasis, which includes both superficial infections and invasive disease, is the most common cause of fungal infection worldwide. Candida bloodstream infections (BSI) cause significant mortality and elicit a major threat to... Read more »

Burden and Impact of Plasmodium Vivax in Pregnancy: A Multi-Centre Prospective Observational Study

More than a third of the world′s population is at risk of Plasmodium vivax infection, 90% of whom live in the Asia and the Pacific regions, while the rest live in the American (6%) and African (3%) regions. In comparison with P. falciparum, P. vivax infection has received little attention mostly because it has been considered a relatively benign disease... Read more »

The microbiome composition of Aedes aegypti is not critical for Wolbachia-mediated inhibition of dengue virus

Dengue virus (DENV) is an RNA arbovirus and the causative agent of dengue fever and the more severe dengue haemorrhagic fever. There are four serotypes of DENV (DENV1-4), which together are estimated to infect 390 million people per year. Currently there are no... Read more »

Cost-Effectiveness of Hepatitis C Treatment Using Generic Direct-Acting Antivirals Available in India

Hepatitis C virus (HCV) infects more than 70 million people worldwide and between 6–11 million in India. Chronic HCV infection is the leading cause for cirrhosis, hepatocellular carcinoma and... Read more »

Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum

Depending on the geographical location, visceral leishmaniasis can either be caused by Leishmania donovani (East Africa and Indian subcontinent) or L. infantum (Mediterranean basin, central Asia and Latin America). Although both species are closely related and belong to the same complex (L. donovani complex), transmission of L. donovani is mostly anthroponotic while... Read more »

Cholera Forecast for Dhaka, Bangladesh, with the 2015-2016 El Niño: Lessons Learned

Climate variability, specifically the El Niño-Southern Oscillation, has been shown to influence the year-to-year variation of seasonal outbreaks of cholera in Bangladesh. In particular, interannual variations of the disease have been shown to be positively associated with... Read more »

Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients

The success of Mycobacterium tuberculosis as a human pathogen is largely due to its ability to switch between latent and active states and to adapt to different environments and stresses. These adaptations are reflected by... Read more »

Interventions For Treating Patients With Chikungunya Virus Infection-Related Rheumatic and Musculoskeletal Disorders

Chikungunya virus infection is caused by an alphavirus transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Three reports from the mid-1950s describe an outbreak of viral disease observed in... Read more »

Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays

The burden of malaria in India has halved over the last 15 years, yet India continues to account for over 70% of malaria cases in South East Asia. The ‘National Framework for Malaria Elimination in India 2016–2030’ has two aims: eliminating malaria throughout the country by... Read more »

Asymptomatic leishmaniasis in kala-azar endemic areas of Malda district, West Bengal, India

Visceral leishmaniasis is a vector-borne protozoal disease caused by the Leishmania donovani species complex. Estimated 200,000–400,000 new cases are recorded per year worldwide of which 67% of the total cases are contributed by three Asian countries... Read more »

Comparison of TST and IGRA in Diagnosis of Latent Tuberculosis Infection in a High TB-Burden Setting

According to the World Health Organization Global TB report, 2015 approximately one- third of the world population is infected with Mycobacterium tuberculosis. Although individuals with LTBI are asymptomatic, however, they constitute an important... Read more »

Molecular Mimicry between Chikungunya Virus and Host Components: A Possible Mechanism for the Arthritic Manifestations

Chikungunya fever is caused by a arbovirus belonging to Family Togaviridae and Genus Alphavirus. CHIKV is positive sense RNA virus with about 11.8 kb long genome. The prevalence of CHIKV has increased globally. It caused massive outbreaks when... Read more »

Priority-Setting for Novel Drug Regimens to Treat Tuberculosis: An Epidemiologic Model

The number of available or prospective drugs for treating tuberculosis (TB) is undergoing a long-overdue expansion. Delamanid and bedaquiline, both recently approved for the treatment of multidrug-resistant TB, are the first novel agents registered for TB treatment in... Read more »

Widespread fear of dengue transmission but poor practices of dengue prevention

Dengue is an infectious viral disease transmitted by a domesticated mosquito, Aedes aegypti. There are supposedly 50 to 400 million people infected each year by dengue virus, developing various clinical spectrum of dengue infection that includes... Read more »

Gender Differences in Factors Related to HIV Risk Behaviors among People Who Inject Drugs in North-East India

Injection drug use is an important driver of HIV epidemics in different regions of the world including India, which is home to 168,000–1.1 million people who inject drugs with a high prevalence of HIV and... Read more »

Control of Aedes aegypti Breeding: A Novel Intervention for Prevention and Control of Dengue in an Endemic Zone of Delhi, India

Dengue, a fast spreading vector borne disease is endemic in more than 100 countries with half of world’s population living in area at risk of this disease... Read more »

Unravelling the Molecular Epidemiology and Genetic Diversity among Burkholderia pseudomallei Isolates from South India Using Multi-Locus Sequence Typing

Melioidosis, caused by soil saprophytic bacteria Burkholderia pseudomallei is a fatal infection among human and animals of the tropics. Numerous factors such as the... Read more »

Zika Virus Infection as a Cause of Congenital Brain Abnormalities and Guillain–Barré Syndrome: Systematic Review

An “explosive pandemic of Zika virus infection” in 2015 caught the world by surprise. The Pan American Health Organization and World Health Organization published an alert about a possible association with increases in reports of congenital abnormalities and Guillain–Barré syndrome... Read more »
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