Psoriasis guidelines provide updates on pharmacotherapy, guidance on special populations

New consensus guidelines for the management of plaque psoriasis include updates on pharmacotherapy options and the treatment of special populations such as children, pregnant women and their partners, nursing mothers, the elderly, and patients diagnosed with cancer, HIV, or hepatitis B or C. Key Point: Biologics and other immunosuppressive agents… 

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Posted in Dermatology, Pharmacology | Tagged , , , , , , , , , , | Volume: | Leave a comment

Proton-pump inhibitors may be linked to increased risk of C. difficile-associated diarrhea

Proton-pump inhibitors (PPIs) may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD). Doctors and patients are being warned that if a patient develops diarrhea that does not improve while receiving a PPI, then CDAD should be considered as a diagnosis and managed appropriately, according to an advisory… 

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Posted in Gastroenterology, Infectious Disease, Pharmacology, Primary Care | Tagged , , , , , , , , , , , , , | Volume: | Leave a comment

Parent education key to improving pediatric vaccination rates in India

The greatest barrier to routine immunization of children in India is parents’ lack of awareness of the importance of vaccination, according to a recent study of pediatricians and primary health center (PHC) physicians. Key Point: Parents should be educated as to the importance of fully vaccinating their children. A focused… 

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Posted in Infectious Disease, Pediatrics, Primary Care | Tagged , , , , , , , , | Volume: | Leave a comment

Study identifies risk factors for prolonged diarrheal duration, complications in children

A new pediatric study has found that younger age, malnourishment, dehydration, fever, dysentery (bloody stool), longer duration of diarrhea prior to admission, and the failure to treat diarrhea with medication put children suffering an acute bout of diarrhea at increased odds of experiencing a prolonged course or complication. Key Point:… 

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Posted in Infectious Disease, Pediatrics, Primary Care | Tagged , , , , , , , , , , , | Volume: | Leave a comment

Study draws attention to potential gender disparities in cardiovascular care in India

Cardiovascular disease is a leading cause of morbidity and mortality among women in many parts of India, according to data from the World Health Organization (WHO) and the Andhra Pradesh Rural Health Initiative. Now in a paper published recently in the journal Heart, members of the George Institute for Global… 

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Posted in Cardiology, Cardiovascular Disease, Nutrition, Pharmacology, Primary Care, Women's Health | Tagged , , , , , , , , , , , , | Volume: | Leave a comment

Clopidogrel plus aspirin can cause more harm than good in small subcortical stroke prevention

Adding clopidogrel to aspirin as an anti-blood clot regimen is unlikely to prevent recurrent small subcortical strokes and also may increase the risk of bleeding and death in patients with subcortical stroke (S3), according to a recent study that investigators stopped early due to these findings. Key Point: Adding clopidogrel… 

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Posted in Hypertension, Neurology, Non-Communicable Disease, Pharmacology, Primary Care | Tagged , , , , , , , , , , , , , | Volume: | Leave a comment

New mechanisms of hypertension in pregnancy help determine patients at risk

A new review sheds some light on some of the potential metabolic and endocrine causes of preeclampsia, which is one of the most common conditions complicating pregnancy. Preeclampsia, which is characterized by high blood pressure and protein in the urine, can cause strokes, kidney and liver damage, and death. “Endothelial… 

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Posted in Endocrinology, Hypertension, Ob/Gyn | Tagged , , , , , , , , , , | Volume: | 1 Response