Routine use of antibiotics not warranted in most cases of rhinosinusitis

Antibiotic treatment is no better than placebo at improving symptoms in patients with acute uncomplicated rhinosinusitis, according to a study recently published in the Journal of the American Medical Association (JAMA). Key Point: Routine antibiotics for acute rhinosinusitis do not improve symptoms and are not warranted. Watchful waiting is a… 

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Posted in Allergy and Immunology, Pharmacology, Primary Care | Tagged , , , , , , , , | Volume: | Leave a comment

Presence of risk factors at middle age defines future cardiovascular risk

Risk factors present at middle age define an individual’s lifetime risk for cardiovascular disease, according to results from a meta-analysis conducted by U.S. researchers. Key Point: Risk factors present at middle age predict lifetime risk of cardiovascular disease, which reinforces the importance of preventive care. As part of the Cardiovascular… 

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Posted in Cardiology, Cardiovascular, Cardiovascular Disease, Diabetes, Hypertension, Non-Communicable Disease, Primary Care | Tagged , , , , , , , , , | Volume: | Leave a comment

High fiber diet does not protect against asymptomatic diverticulosis

Going against a longstanding belief, a high-fiber diet does not protect against asymptomatic diverticulosis. To the contrary, the prevalence of the disease actually appears to be greater in those on a high-fiber diet, according to a recently published study. Key Point: This study does not support recommending a high-fiber diet… 

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Posted in Gastroenterology, Nutrition, Primary Care | Tagged , , , , , , , , | Volume: | Leave a comment

5-alpha reductase inhibitor slows progression of low-risk prostate cancer tumors

Active surveillance added to treatment with the 5-alpha reductase inhibitor dutasteride slowed the progression of cancerous prostate tumors in men with low-risk localized disease, according to researchers from the University of Toronto in Ontario, Canada. Key Point: Active surveillance in combination with dutasteride is a reasonable strategy for the treatment… 

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Posted in Oncology, Pharmacology, Urology | Tagged , , , , , | Volume: | Leave a comment

Outcomes equal between medical therapy and cardiac stents in stable coronary artery disease

Optimal medical therapy works equally as well as implanting a coronary artery stent in patients with stable coronary artery disease to prevent death, nonfatal myocardial infarction (MI), unplanned revascularization, or angina, a new meta-analysis has found. With coronary artery disease (CAD) on the rise in India, industry estimates place the… 

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Posted in Cardiology, Cardiovascular, Cardiovascular Disease, Primary Care | Tagged , , , , , , , , , , , | Volume: | 1 Response

Warfarin no better than aspirin in patients with heart failure

mdCurrent Conference Report: International Stroke Conference Warfarin did not reduce the rate of the combined endpoint of death, ischemic stroke, or intracerebral hemorrhage compared with aspirin, according to a Late Breaking Clinical Trial presented at the 2012 International Stroke Conference. Both warfarin and aspirin are used in this clinical setting,… 

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Posted in Cardiology, Cardiovascular, Cardiovascular Disease, Neurology, Non-Communicable Disease, Pharmacology, Primary Care | Tagged , , , , , , , , , , , , | Volume: | Leave a comment

Meta-analysis examines whether aspirin is worth the risk for primary prevention

Despite clinically relevant reductions in nonfatal myocardial infarction (MI), the use of aspirin in patients without a history of cardiovascular disease (CVD) does not lead to reductions in either cardiovascular- or cancer-related death, according to a recently published meta-analysis. The incidence of CVD in India is on the rise and… 

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Posted in Cardiology, Cardiovascular Disease, Pharmacology | Tagged , , , , , , , , , | Volume: | Leave a comment