Oral misoprostol is as effective as intravenous oxytocin in labor augmentation

Oral misoprostol is an effective agent to augment labor compared with intravenous oxytocin, according to a study published recently in Obstetrics & Gynecology. India has the largest number of births per year in the world, 27 million, with greater than 60% occurring at home, according to the World Health Organization…. 

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Benefits outweigh the risks for antimalarial treatment of women in the first trimester of pregnancy

Malaria caused by either Plasmodium vivax or Plasmodium falciparum increases miscarriage risk during the first trimester. Antimalarial treatment is important and chloroquine, quinine, and mefloquine do not significantly increase the risk of miscarriage or other adverse events, according to a population-based study. “This paper confirms the dictum that malaria in… 

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Posted in Infectious Disease, Ob/Gyn | Tagged , , , , , , , , | Volume: | 1 Response

Excessive vitamin D correlated with higher blood levels of the inflammatory marker C-reactive protein

The inverse association between serum vitamin D level and the serum level of the inflammatory marker C-reactive protein (CRP) is apparent only at low levels of vitamin D. At levels of serum vitamin D above the median, serum CRP actually increases, a recent study found. CRP, which measures general levels… 

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Posted in Cardiology, Cardiovascular, Cardiovascular Disease, Nutrition, Primary Care | Tagged , , , , , , , , | Volume: | Leave a comment

Treat tuberculosis in pregnancy using first-line agents, but wait for second-line agents

Beware of false-positive skin tests in pregnant women vaccinated with BCG (Bacille Calmette Guerin vaccine for tuberculosis [TB]), in those previously treated for TB infection, or in those previously infected with other Mycobacterium species. False negatives can occur in those with compromised immune systems (eg, HIV) or due to technical… 

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Antiviral therapy may not be enough to suppress genital herpes reactivation

Even high-dose antiherpetic therapy may not be enough to quell short bursts of subclinical genital herpes simplex virus (HSV) reactivation, which may account for the continued transmission of HSV despite suppressive antiviral therapy. Researchers from the University of Washington, Seattle, United States, conducted 3 separate but complementary open-label crossover studies… 

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Posted in Infectious Disease, Ob/Gyn, Pharmacology, Primary Care, Urology | Tagged , , , , , , , , , , , , | Volume: | Leave a comment

Increased education increases likelihood of longer lifespans

Among older adults in India and other low- and middle-income countries, a higher education status is a consistent independent predictor against death. This finding comes from a study of 12,373 people aged 65 years and older living in India, China, and 6 Latin American low- to middle-income countries. The participants… 

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Forceps-assisted delivery associated with fewer neurologic complications

Forceps-assisted vaginal deliveries appear to be associated with fewer total neurologic complications, including seizure, than either vacuum-assisted or Cesarean deliveries, a recent study found. However, forceps-assisted delivery, compared with the other delivery methods, was associated with a higher incidence of brachial plexus injury and facial nerve palsy. “Vacuum-assisted deliveries are… 

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Posted in Neurology, Neurology Featured 2, Ob/Gyn, Pediatrics | Tagged , , , , , , , , , , , , , , , , | Volume: | 1 Response