Key Point: Donepezil’s cardiac safety profile appears promising in this small-scale, short-term study. If drugs with a similar mechanism of action that affect acetylcholine are prescribed in patients receiving this therapy, patients should be closely monitored for potential cardiac effects. However, these effects have not been significantly demonstrated in patients…
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The spread of dengue fever is a significant problem, mostly due to increased global trade and travel. It is estimated to cause 50 million infections yearly, with outbreaks in India becoming more commonplace. Infections often occur in urban areas and spread into neighboring communities. Over the last 20 years, higher…
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Algorithms that predict risk for venous thromboembolism occurring outside of the hospital setting should be reevaluated to include infection, erythropoiesis-stimulating agents, and blood transfusion, in addition to the more commonly recognized triggers such as major surgeries, fractures, immobility, and chemotherapy, according to a recent study. “The notion that VTE occurs…
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Increased access to improved water sources and improved sanitation are each associated with a significant decrease in mortality in children younger than 5 years, mortality due to diarrhea in children younger than 5 years, infant mortality, and maternal mortality. These were the findings of a large observational study that included…
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Delayed post-partum pre-eclampsia and eclampsia remain risks for maternal health in the week following delivery, regardless of whether there is a maternal history of hypertension or whether hypertensive disease has developed prior to hospital discharge, according to a recent study. “The sudden appearance of post-partum eclampsia can be a rude…
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Pre-term delivery and low birth weight for gestational age each individually increase the risk of maternal hospitalization or death from cardiovascular disease (CVD) later in life, according to a recent study published in Circulation. CVD was defined as coronary heart disease, cerebrovascular events, and/or heart failure. “Management of pre-term and…
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Longstanding diabetes increases risk of stroke
Strokes are much more likely in patients who have had diabetes for 10 or more years compared with those without diabetes, according to findings from the Northern Manhattan Study, a research study of stroke and stroke risk factors. “The findings emphasize the chronic nature of diabetes and the fact that…
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