Clopidogrel plus aspirin can cause more harm than good in small subcortical stroke prevention

Adding clopidogrel to aspirin as an anti-blood clot regimen is unlikely to prevent recurrent small subcortical strokes and also may increase the risk of bleeding and death in patients with subcortical stroke (S3), according to a recent study that investigators stopped early due to these findings. Key Point: Adding clopidogrel… 

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Posted in Hypertension, Neurology, Non-Communicable Disease, Pharmacology, Primary Care | Tagged , , , , , , , , , , , , , | Volume: | Leave a comment

New mechanisms of hypertension in pregnancy help determine patients at risk

A new review sheds some light on some of the potential metabolic and endocrine causes of preeclampsia, which is one of the most common conditions complicating pregnancy. Preeclampsia, which is characterized by high blood pressure and protein in the urine, can cause strokes, kidney and liver damage, and death. “Endothelial… 

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Posted in Endocrinology, Hypertension, Ob/Gyn | Tagged , , , , , , , , , , | Volume: | 1 Response

Severe or nonsevere depressed patients benefit from antidepressant medication

Patients diagnosed with nonsevere depression can benefit from antidepressant medication, a recently published study has found. This finding, which is contrary to the findings of previous meta- or mega-analyses, was based on the reanalysis of 6 randomized placebo-controlled antidepressant studies conducted at a large psychiatric hospital’s outpatient clinic from 1977… 

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Posted in Pharmacology, Primary Care, Psychiatry | Tagged , , , , , , , , , , , , | Volume: | Leave a comment

Study ties H pylori infection to increased diabetes risk

Infection with Helicobacter pylori more than doubles the risk of developing diabetes, according to the results of a recently published study. The authors note that this finding is consistent with prior reports showing an association between H pylori and the prevalence of diabetes in cross-sectional studies. Key Point: Serologic evidence… 

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Posted in Diabetes, Gastroenterology, Infectious Disease, Primary Care | Tagged , , , , , , | Volume: | Leave a comment

Zinc reduces mortality in severe childhood pneumonia

Zinc gluconate supplementation in children between the ages of 6 months and 59 months with severe pneumonia significantly reduced case fatality rates, but was not associated with faster normalization of children’s respiratory rate, body temperature, or oxygen saturation. According to UNICEF and the Public Health Foundation of India, childhood pneumonia… 

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Posted in Infectious Disease, Nutrition, Pediatrics | Tagged , , , , , , , , , , , | Volume: | Leave a comment

Proton-pump inhibitors linked to hip fractures in women, especially smokers

Regular use of proton-pump inhibitors (PPIs) can increase the risk for hip fracture in postmenopausal women, especially those with a history of smoking, according to a study published recently in the British Medical Journal (BMJ). Key Point: Postmenopausal women who are regular users of PPIs have an increased risk of… 

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Posted in Gastroenterology, Geriatrics, Non-Communicable Disease, Orthopedics, Women's Health | Tagged , , , , , , , , , | Volume: | Leave a comment

Vitamin D, but not calcium, associated with fewer stress fractures in girls

Vitamin D is associated with a lower risk of developing stress fractures, especially among very active girls who engage in at least 1 hour of high-impact activity per day. Vitamin D deficiency is common in all ages in India, according to recent studies. Marwaha and Sripathy noted a high prevalence… 

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Posted in Nutrition, Orthopedics, Pediatrics | Tagged , , , , , , | Volume: | Leave a comment
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