Category Archives: Pharmacology

Pharmacology in the news as well as the latest learned articles and clinical research related to medicines, their efficacy and usages in the treatment of health conditions and disease.

Incorrect paracetamol dosing common among children’s caregivers

Giving supratherapeutic doses of paracetamol is common among caregivers, according to a recent study in the Journal of Family Medicine and Primary Care. “Doctors should check the understanding of the [caregiver] by asking a simple question, after explaining the dosing procedures: ‘What did you understand? Please, let me know in… 

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Also posted in Pediatrics, Primary Care | Tagged , , , , , , | Volume: | Leave a comment

Recommendations focus on managing thyroid disease in pregnancy

Treating thyroid disease during pregnancy can benefit the mother, fetus, and the intellectual development of the child, according to the introduction to the newest guidelines from the American Thyroid Association Task Force on Thyroid Disease During Pregnancy and Postpartum. Of particular concern is detecting and treating subclinical hypothyroidism (SCH), in… 

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Also posted in Endocrinology, Ob/Gyn, Primary Care | Tagged , , , , , , , , , , , , | Volume: | Leave a comment

New guidelines compare oral agents for diabetes management

An estimated 50.8 million people in India are living with diabetes, according to the World Diabetes Foundation. Diabetes results in complications ranging from retinopathy and neuropathy to coronary artery disease. Epidemiological demand combined with increased complexity of care make evidence-based treatment guidelines vital for busy clinicians. The American College of… 

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Also posted in Diabetes, Primary Care | Tagged , , , , , , , , , , , , , , , , , , , | Volume: | 1 Response

Statins may slow knee OA, but no effect seen at the hip

Statin use may slow the progression of osteoarthritis (OA) of the knee but does not appear to affect the rate of OA progression in the hip, according to a recently published prospective observational study. For the analysis, x-rays of the hip and knee were examined at baseline and again an… 

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Also posted in Geriatrics, Orthopedics, Primary Care | Tagged , , , , , , , , , | Volume: | Leave a comment

Steroid injections do not significantly improve back pain

Lumbosacral radiculopathy does not improve significantly more with epidural steroids vs saline injections 1 month following treatment, according to results from a multicenter, randomized trial. The study also looked at functional capacity, and injections of etanercept fared worse than steroids or saline. In the study, which was conducted in the… 

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Also posted in Orthopedics, Primary Care | Tagged , , , , , , , , , , | Volume: | Leave a comment

Galectin-3 identifies subset of heart failure patients who can benefit from a statin

Blood levels of the carbohydrate-binding protein galectin-3 identified patients with ischemic heart failure who derived significant clinical benefit from rosuvastatin in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) trial. A substudy of CORONA demonstrated that patients with blood levels of galectin-3 <19.0 ng/mL at the start of the… 

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Also posted in Cardiovascular Disease, Primary Care | Tagged , , , , , , , , , , | Volume: | Leave a comment

Prolonged venous thromboembolism prophylaxis with aspirin appears safe and effective

While once thought to be rare, recent data published by Lee and colleagues suggest the incidence of venous thromboembolism (eg, deep vein thrombosis or pulmonary embolism) is on the rise in India, accounting for about 17.5 per 10,000 hospital admissions. Unfortunately, approximately 20% of patients experiencing an unprovoked venous thromboembolism… 

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Also posted in Cardiovascular Disease | Tagged , , , , , , , , , | Volume: | Leave a comment