Category Archives: Pharmacology

Pharmacology in the news as well as the latest learned articles and clinical research related to medicines, their efficacy and usages in the treatment of health conditions and disease.

Pediatric multidrug-resistant tuberculosis gets more attention

Due to difficulties in establishing accurate diagnoses and lower priorities assigned by tuberculosis (TB) control programs, pediatric TB has been relatively neglected. Treatment delays lead to the progression of disease, increased risk of infectiousness, greater complications, and higher rates of morbidity and death. “The key learnings identified from this study… 

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Also posted in Infectious Disease, Pediatrics, Primary Care | Tagged , , , , , , , , , , , | Volume: | Leave a comment

Large proportion of antimalarial drugs fail chemical and packaging analysis

In Southeast Asia and Sub-Saharan Africa, 35% of antimalarial drugs failed chemical analysis, highlighting the need to identify and prevent criminal production and distribution of antimalarial drugs, according to a recent analysis of published and unpublished studies. Malaria is an endemic infection in 106 countries, including India. Although infection rates… 

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Also posted in Infectious Disease, Primary Care | Tagged , , , , , , | Volume: | Leave a comment

NSAID use may be associated with decreased risk of skin cancer

A meta-analysis has found that the use of NSAIDs—including ibuprofen, aspirin, and naproxen—was associated with a decreased risk of skin cancer. “This study is interesting, but a concern of long-term use of NSAIDs includes renal and gastric complications.” -Saumen Chaudhuri, MD, medical officer, State Public Health Services, South Dinajpur Hospital,… 

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Also posted in Dermatology, Oncology, Primary Care | Tagged , , , , , , , , , , , | Volume: | Leave a comment

Use of beta-blockers and aspirin in cancer patients with acute myocardial infarction prolongs survival

In patients with cancer who had an acute myocardial infarction (AMI) the use of beta-blockers and aspirin were each associated with improved survival. The population was primarily comprised of patients with non-ST-segment elevation myocardial infarction (NSTEMI). This was the main finding of a recent observational study published in Clinical Cardiology…. 

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Also posted in Cardiovascular Disease, Oncology | Tagged , , , , , , , | Volume: | Leave a comment

Antipsychotic medications help prevent relapses in schizophrenia, but increase side effects too

Taking another step in the discussion about the benefits of antipsychotic medications vs side effects such as weight gain, a recently published meta-analysis examined 116 reports involving 65 trials and data for 5,493 patients. Using a primary outcome of relapse between 7 and 12 months, the researchers found that use… 

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Also posted in Neurology, Primary Care, Psychiatry | Tagged , , , , , , , , | Volume: | Leave a comment

Doxycycline may provide significant protection against Clostridium difficile infections

Hospitalized patients who receive doxycycline in addition to ceftriaxone have a 79% reduced risk of Clostridium difficile infection vs patients who receive ceftriaxone only, a recent study found. “In India, the true prevalence of [C. difficile] is not known because a majority of the hospitals do not investigate for this… 

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Also posted in Gastroenterology, Primary Care, Women's Health | Tagged , , , , , , , , , , | Volume: | Leave a comment

Hormone replacement therapy may increase the risk of ulcerative colitis in postmenopausal women

mdCurrent Conference Report: Digestive Disease Week Hormone replacement therapy (HRT) may increase the risk of ulcerative colitis in postmenopausal women, according to a new study presented at Digestive Disease Week 2012. “It is important that clinicians are aware of the results of this study, but it should not lead to… 

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Also posted in Gastroenterology, mdCurrent Conference Reports, Primary Care, Women's Health | Tagged , , , , , , , , , , , | Volume: | 1 Response