Category Archives: Oncology

Cancer and its prevalance, diagnosis and treatment in India and around the world including news, research and the latest learned articles on oncology.

PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide

PI3K is crucial signal transducing enzyme regulating cell proliferation, cell survival, differentiation, apoptosis and angiogenesis. It is essential for activation of AKT which plays a central role in both physiological and…

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Establishment of 3D Co-Culture Models from Different Stages of Human Tongue Tumorigenesis: Utility in Understanding Neoplastic Progression

All normal tissues rely on a continuous sequence of cellular interactions in a microenvironment comprising several growth factors, hormones, adhesion molecules and an intricate extracellular molecular matrix for their growth and maintenance…

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Impact of Maspin Polymorphism rs2289520 G/C and Its Interaction with Gene to Gene, Alcohol Consumption Increase Susceptibility to Oral Cancer Occurrence

Oral cancer is lethal and usually causes spacious impairment to the organs involved including lesions of lip, tongue, major salivary glands, gums and adjacent oral cavity tissues…

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A Functional rs353293 Polymorphism in the Promoter of miR-143/145 Is Associated with a Reduced Risk of Bladder Cancer

Epidemiological studies have identified some risk factors for BC, such as tobacco smoking, occupational exposures to industrial chemicals, and dietary nitrates and arsenic…

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Pro-Oxidant Role of Silibinin in DMBA/TPA Induced Skin Cancer: 1H NMR Metabolomic and Biochemical Study

The Indian subcontinent reports higher prevalence of SCC in comparison to BCC. Apart from ultraviolet radiation (UVR), the other common causes of NMSC are environmental and…

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Associations between Diabetes and Quality of Life among Breast Cancer Survivors

Previous studies reported that the comorbidity of diabetes may be a risk factor influencing the quality of life (QOL) of patients with breast cancer. Diabetes can shorten the disease-free survival of breast cancer patients and…

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Immunotherapy for Oncological Cancer: ASCO Focus

Dr. Jamal’s DENVAX is a Dendritic Cell (DC)-based cancer immunotherapy that prevents to the recurrence of cancer after surgery, chemotherapy or radiation because the immune system will need to recognize and attack a smaller number of cancer cells, which was the main theme of the ASCO event…

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