Category Archives: Oncology

Cancer and its prevalance, diagnosis and treatment in India and around the world including news, research and the latest learned articles on oncology.

Study of association and molecular analysis of human papillomavirus in breast cancer of Indian patients: Clinical and prognostic implication

Human papillomavirus is a DNA virus having a 9.2Kb genome. The high-risk subtypes were frequently associated with different cancers, primarily cervical cancer and Head and neck squamous cell carcinoma. Among the subtypes of…

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Cancer and Diabetes: The Disharmonious Disease Alliance

We need to battle against cancer and diabetes together and in fact, prevention as well as control measures need to be addressed…

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Role of PXR in Hepatic Cancer: Its Influences on Liver Detoxification Capacity and Cancer Progression

Pregnane and Xenobiotic Receptor, acts as a ‘master-regulator’ of expression of components of the detoxification machinery thereby defending the body from the toxic chemical insults…

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Effect of Preoperative Risk Group Stratification on Oncologic Outcomes of Patients with Adverse Pathologic Findings at Radical Prostatectomy

Prostate cancer (PC) has become the most common non-dermatologic cancer among Western men. Due to prostate-specific antigen screening efforts, increasing numbers of PC cases are diagnosed when the tumor is still confined to…

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PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide

PI3K is crucial signal transducing enzyme regulating cell proliferation, cell survival, differentiation, apoptosis and angiogenesis. It is essential for activation of AKT which plays a central role in both physiological and…

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Establishment of 3D Co-Culture Models from Different Stages of Human Tongue Tumorigenesis: Utility in Understanding Neoplastic Progression

All normal tissues rely on a continuous sequence of cellular interactions in a microenvironment comprising several growth factors, hormones, adhesion molecules and an intricate extracellular molecular matrix for their growth and maintenance…

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Impact of Maspin Polymorphism rs2289520 G/C and Its Interaction with Gene to Gene, Alcohol Consumption Increase Susceptibility to Oral Cancer Occurrence

Oral cancer is lethal and usually causes spacious impairment to the organs involved including lesions of lip, tongue, major salivary glands, gums and adjacent oral cavity tissues…

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