Category Archives: Infectious Disease

The list of infectious diseases which occur with significant frequency in India is long and alarming. It is in the interest of local doctors and clinicians to stay abreast of international news and research on the diagnosis and treatment of infectious diseases such as bacterial diarrhea, hepatitis A and E, typhoid fever, chikungunya, dengue fever, yellow fever Japanese encephalitis, malaria, rabies and leptospirosis

No increase in intussusception after RotaTeq immunization

Infants given RotaTeq, a rotavirus vaccine, had no increased risk of intussusception after immunization compared with infants not given RotaTeq, according to the 4-year Vaccine Safety Datalink (VSD) study. The multiple-site study, conducted in the United States and published earlier this year in the Journal of the American Medical Association,… 

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Also posted in Pediatrics, Primary Care | Tagged , , , , , , , , , , , | Volume: | Leave a comment

Zinc reduces treatment failure in children experiencing serious bacterial infections

Of the more than 1 million infant deaths that occur each year in India, more than 25% are associated with serious bacterial infections, including pneumonia, sepsis, and meningitis. Zinc deficiency has been linked to higher rates of infection and is a common problem for Indian children, particularly during their first… 

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Treat tuberculosis with triple therapy, using the correct dose and duration to prevent resistant organisms

More than 400,000 people die of tuberculosis (TB) in India every year. Drug-resistant TB is due to inappropriate drug and dose prescribing, and/or lack of patient medication adherence. Careless management has led to the emergence of progressively more resistant TB to anti-TB medications. “Drug-resistant tuberculosis, the dreaded form of the… 

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Macrolide antibacterial agent fidaxomicin may be an alternative to vancomycin for Clostridium difficile-associated diarrhea

Fidaxomicin, a macrolide antibiotic, is noninferior to vancomycin in the treatment of Clostridium difficile diarrhea in terms of clinical cure. This was the main finding of a recent randomized trial that sought to demonstrate the noninferiority of fidaxomicin for this indication. C difficile, which causes 15% to 25% of antibiotic-associated… 

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Also posted in Gastroenterology, Pharmacology, Primary Care | Tagged , , , , , , , , | Volume: | Leave a comment

Statin therapy has modest effect in preventing pneumonia

Statin therapy may modestly reduce the risk of pneumonia in healthy adults, researchers have found in a subanalysis of the JUPITER study. Key Point: This study offers support for the continued research of statin therapy in the prevention of infection, including lung infection. The use of statins, the first-line therapy… 

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Also posted in Cardiovascular Disease, Pharmacology | Tagged , , , , , , , , | Volume: | Leave a comment

New dengue fever classification differentiates typical and severe infections to improve patient triage and management

The spread of dengue fever is a significant problem, mostly due to increased global trade and travel. It is estimated to cause 50 million infections yearly, with outbreaks in India becoming more commonplace. Infections often occur in urban areas and spread into neighboring communities. Over the last 20 years, higher… 

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Benefits outweigh the risks for antimalarial treatment of women in the first trimester of pregnancy

Malaria caused by either Plasmodium vivax or Plasmodium falciparum increases miscarriage risk during the first trimester. Antimalarial treatment is important and chloroquine, quinine, and mefloquine do not significantly increase the risk of miscarriage or other adverse events, according to a population-based study. “This paper confirms the dictum that malaria in… 

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Also posted in Ob/Gyn | Tagged , , , , , , , , | Volume: | 1 Response