Category Archives: Infectious Disease

The list of infectious diseases which occur with significant frequency in India is long and alarming. It is in the interest of local doctors and clinicians to stay abreast of international news and research on the diagnosis and treatment of infectious diseases such as bacterial diarrhea, hepatitis A and E, typhoid fever, chikungunya, dengue fever, yellow fever Japanese encephalitis, malaria, rabies and leptospirosis

Burden and Impact of Plasmodium Vivax in Pregnancy: A Multi-Centre Prospective Observational Study

More than a third of the world′s population is at risk of Plasmodium vivax infection, 90% of whom live in the Asia and the Pacific regions, while the rest live in the American (6%) and African (3%) regions. In comparison with P. falciparum, P. vivax infection has received little attention mostly because it has been considered a relatively benign disease…

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Painless Swelling of the Forefoot and Recurrent Subcutaneous Abscesses of the Lower Leg—Two Distinct Presentations Illustrating the Spectrum of Eumycetoma in a Nonendemic Country

Eumycetoma is a neglected tropical disease that is characterized by chronic progressive local inflammation of subcutaneous tissues with sinus formation and purulent discharge. Although the infection evolves from a small subcutaneous nodule, patients often present late with advanced disease, including…

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The microbiome composition of Aedes aegypti is not critical for Wolbachia-mediated inhibition of dengue virus

Dengue virus (DENV) is an RNA arbovirus and the causative agent of dengue fever and the more severe dengue haemorrhagic fever. There are four serotypes of DENV (DENV1-4), which together are estimated to infect 390 million people per year. Currently there are no…

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Cost-Effectiveness of Hepatitis C Treatment Using Generic Direct-Acting Antivirals Available in India

Hepatitis C virus (HCV) infects more than 70 million people worldwide and between 6–11 million in India. Chronic HCV infection is the leading cause for cirrhosis, hepatocellular carcinoma and…

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Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum

Depending on the geographical location, visceral leishmaniasis can either be caused by Leishmania donovani (East Africa and Indian subcontinent) or L. infantum (Mediterranean basin, central Asia and Latin America). Although both species are closely related and belong to the same complex (L. donovani complex), transmission of L. donovani is mostly anthroponotic while…

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Cholera Forecast for Dhaka, Bangladesh, with the 2015-2016 El Niño: Lessons Learned

Climate variability, specifically the El Niño-Southern Oscillation, has been shown to influence the year-to-year variation of seasonal outbreaks of cholera in Bangladesh. In particular, interannual variations of the disease have been shown to be positively associated with…

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Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients

The success of Mycobacterium tuberculosis as a human pathogen is largely due to its ability to switch between latent and active states and to adapt to different environments and stresses. These adaptations are reflected by…

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