Category Archives: Infectious Disease Featured 2

Cost-Effectiveness of Hepatitis C Treatment Using Generic Direct-Acting Antivirals Available in India

Hepatitis C virus (HCV) infects more than 70 million people worldwide and between 6–11 million in India. Chronic HCV infection is the leading cause for cirrhosis, hepatocellular carcinoma and…

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Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum

Depending on the geographical location, visceral leishmaniasis can either be caused by Leishmania donovani (East Africa and Indian subcontinent) or L. infantum (Mediterranean basin, central Asia and Latin America). Although both species are closely related and belong to the same complex (L. donovani complex), transmission of L. donovani is mostly anthroponotic while…

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Cholera Forecast for Dhaka, Bangladesh, with the 2015-2016 El Niño: Lessons Learned

Climate variability, specifically the El Niño-Southern Oscillation, has been shown to influence the year-to-year variation of seasonal outbreaks of cholera in Bangladesh. In particular, interannual variations of the disease have been shown to be positively associated with…

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Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients

The success of Mycobacterium tuberculosis as a human pathogen is largely due to its ability to switch between latent and active states and to adapt to different environments and stresses. These adaptations are reflected by…

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Interventions For Treating Patients With Chikungunya Virus Infection-Related Rheumatic and Musculoskeletal Disorders

Chikungunya virus infection is caused by an alphavirus transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Three reports from the mid-1950s describe an outbreak of viral disease observed in…

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Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays

The burden of malaria in India has halved over the last 15 years, yet India continues to account for over 70% of malaria cases in South East Asia. The ‘National Framework for Malaria Elimination in India 2016–2030’ has two aims: eliminating malaria throughout the country by…

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Asymptomatic leishmaniasis in kala-azar endemic areas of Malda district, West Bengal, India

Visceral leishmaniasis is a vector-borne protozoal disease caused by the Leishmania donovani species complex. Estimated 200,000–400,000 new cases are recorded per year worldwide of which 67% of the total cases are contributed by three Asian countries…

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