Category Archives: Infectious Disease

The list of infectious diseases which occur with significant frequency in India is long and alarming. It is in the interest of local doctors and clinicians to stay abreast of international news and research on the diagnosis and treatment of infectious diseases such as bacterial diarrhea, hepatitis A and E, typhoid fever, chikungunya, dengue fever, yellow fever Japanese encephalitis, malaria, rabies and leptospirosis

MDR-TB Treatment as Prevention: The Projected Population-Level Impact of Expanded Treatment for Multidrug-Resistant Tuberculosis

Multidrug resistant tuberculosis (MDR-TB) poses one of the greatest threats to TB control worldwide. Not only is the incidence of MDR-TB rising in many areas, curtailing…

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Estimating the Burden of Scrub Typhus: A Systematic Review

Scrub typhus is an infectious disease caused by Orientia tsutsugamushi, an obligate intracellular bacteria, transmitted by the bites of chigger mites…

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Estimating the Incidence of Rotavirus Infection in Children from India and Malawi from Serial Anti-Rotavirus IgA Titres

Prior to wide-spread rotavirus vaccination, rotavirus was responsible for over 450 000 deaths in young children…

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Health Impact and Cost-Effectiveness of a Domestically-Produced Rotavirus Vaccine in India: A Model Based Analysis

Each year, rotavirus gastroenteritis claims the lives of an estimated 215,000 children under five years of age; 22% of these deaths are estimated to…

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Lymphatic Pathology in Asymptomatic and Symptomatic Children with Wuchereria bancrofti Infection in Children from Odisha, India and Its Reversal with DEC and Albendazole Treatment

Treatment with albendazole and either ivermectin or diethylcarbamazine citrate used in the Global Program for Elimination of Lymphatic Filariasis works on the basis of elimination of microfilaria that are infective to the…

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Burden of Bacterial Meningitis in India: Preliminary Data from a Hospital Based Sentinel Surveillance Network

Globally, meningitis is a significant cause of morbidity and mortality in the pediatric population accounting for about 180,000 deaths annually. Prior to introduction of vaccines…

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Safety and Efficacy of Short Course Combination Regimens with AmBisome, Miltefosine and Paromomycin for the Treatment of Visceral Leishmaniasis in Bangladesh

Before the introduction of single-dose AmBisome, miltefosine was included in the National Guidelines of India, Nepal and Bangladesh as a first line treatment for VL following a phase III trial in India that showed a final cure rate of 94%. However, poor compliance due to…

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