Category Archives: Infectious Disease

The list of infectious diseases which occur with significant frequency in India is long and alarming. It is in the interest of local doctors and clinicians to stay abreast of international news and research on the diagnosis and treatment of infectious diseases such as bacterial diarrhea, hepatitis A and E, typhoid fever, chikungunya, dengue fever, yellow fever Japanese encephalitis, malaria, rabies and leptospirosis

Burden of Bacterial Meningitis in India: Preliminary Data from a Hospital Based Sentinel Surveillance Network

Globally, meningitis is a significant cause of morbidity and mortality in the pediatric population accounting for about 180,000 deaths annually. Prior to introduction of vaccines…

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Safety and Efficacy of Short Course Combination Regimens with AmBisome, Miltefosine and Paromomycin for the Treatment of Visceral Leishmaniasis in Bangladesh

Before the introduction of single-dose AmBisome, miltefosine was included in the National Guidelines of India, Nepal and Bangladesh as a first line treatment for VL following a phase III trial in India that showed a final cure rate of 94%. However, poor compliance due to…

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Diagnostic Utility of a Line Probe Assay for Multidrug Resistant-TB in Smear-Negative Pulmonary Tuberculosis

Pulmonary tuberculosis is a major public health disease that ranks as the second-most leading cause of death worldwide, after human immunodeficiency virus infection. In 2016, there were 10.4 million new…

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Comorbidities in Pulmonary Tuberculosis Cases in Puducherry and Tamil Nadu, India: Opportunities for Intervention

An estimated 10.6 million cases of tuberculosis (TB) occur annually in the world, and India accounts for 27% of these. The emergence of drug-resistant TB creates a renewed sense of urgency to control…

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Sub-Therapeutic Nevirapine Concentration During Antiretroviral Treatment Initiation Among Children Living with HIV: Implications for Therapeutic Drug Monitoring

Nevirapine was the first non-nucleoside reverse transcriptase inhibitor approved by the FDA for pediatric use since 1998. Although nevirapine has a low genetic barrier to…

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Identification of Burden Hotspots and Risk Factors for Cholera in India: An Observational Study

Cholera has existed in India for centuries, and is an important public health problem in several parts of the country.. Based on a ten year review from 1997 to 2006, 21 states reported cholera and 12 had multiple outbreaks. During the 10-year period studied, the states having the highest number of…

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Prevalence and Associated Factors of Tuberculosis and Diabetes Mellitus Comorbidity: A Systematic Review

Diabetes mellitus and tuberculosis are major killers of mankind across the globe. The World Health Organization global report for 2015 indicates that, there were 10.4 million new cases and 1.4 million deaths resulting from…

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