Monthly Archives: December 2013

Prenatal arsenic exposure alters gene expression in the adult liver to a proinflammatory state contributing to accelerated atherosclerosis

Environmental exposures during embryonic/fetal development have been shown to disturb the embryonic/fetal developmental program [1]. Some exposures cause severe disturbance of the program and result in gross structural anomalies. Others may have more subtle effects and may contribute to increased susceptibility to chronic adult diseases including cancer, diabetes and cardiovascular disease (CVD).

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Video: SILS appendicectomy with gasless lift laparoscopic surgery

Dr. J. Gnanaraj MS, MCh [Urology], FICS, FARSI, FIAGES is a urologist and laparoscopic surgeon trained at CMC Vellore. He has been appointed as a Professor in the Electronics and Instrumentation Engineering Department of Karunya University and is the Director of Medical Services of the charitable organization SEESHA. He has… 

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Thyroid nodule management

Thyroid nodule management from Balasubramanian Thiagarajan Dr. Balasubramanian Thiagarajan, is a Professor in the Department of Otolaryngology at Stanley Medical College in Chennai, Tamilnadu. He has authored a number of journal articles and case reports on otolaryngology and related topics, as well as three books. Presentation used with permission from… 

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Impact of migration and acculturation on prevalence of type 2 diabetes and related eye complications in Indians living in a newly urbanised society

Type 2 diabetes mellitus (T2DM) is recognised as a major chronic disease affected by lifestyle and behavioural risk factors such as obesity and physical inactivity [1]. There has been a long-standing hypothesis that rising prevalence of T2DM in many countries is related to immigration patterns from developing countries and lifestyle changes from “traditional” to “Western” patterns.

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Multi-scale biomechanical remodeling in aging and genetic mutant murine mitral valve leaflets

Marfan syndrome (MFS) is an autosomal-dominant systemic disorder of connective tissue, with an estimated prevalence of 1 in 5,000 individuals [1]. It is associated with mutations in Fbn1, encoding fibrillin-1, the principal component of extracellular microfibrils, leading to severe cardiovascular, ocular, and skeletal defects [2]. Of these consequences, mitral valve disease is one of the leading indications for surgery and causes of death in young children with MFS.

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Stroke propensity is increased under atrial fibrillation hemodynamics

A simulation study Citation: Choi HW, Navia JA, Kassab GS (2013) Stroke Propensity Is Increased under Atrial Fibrillation Hemodynamics: A Simulation Study. PLoS ONE 8(9): e73485. doi:10.1371/journal.pone.0073485 Published: September 5, 2013 Abstract Atrial fibrillation (AF) is the most common sustained dysfunction in heart rhythm clinically and has been identified as… 

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Fungal sinusitis an update

Fungal sinusitis an update from Balasubramanian Thiagarajan Dr. Balasubramanian Thiagarajan, is a Professor in the Department of Otolaryngology at Stanley Medical College in Chennai, Tamilnadu. He has authored a number of journal articles and case reports on otolaryngology and related topics, as well as three books. Presentation used with permission… 

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