Monthly Archives: July 2012

Interventions can reverse clustering of hypertension and other cardiovascular risk factors

The Indian population is particularly susceptible to cardiovascular (CV) risk factors such as visceral adiposity and insulin resistance. However, few large studies have examined CV risk factors in the Indian population. An understanding the clustering of risk factors can provide vital clues for prevention and treatment. In a recent cross-sectional… 

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Posted in Cardiovascular, Non-Communicable Disease, Primary Care | Tagged , , , , , , , , , , | Volume: | Leave a comment

Blunted morning BP surge may increase risk of cardiovascular events in hypertensive patients

Due to the increased morning incidence of cardiovascular (CV) events, researchers have hypothesized that surges in blood pressure (BP) in the early morning hours may raise the risk of CV events such as myocardial infarction (MI), stroke, and sudden cardiac death. “This study adds to the growing body of information… 

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Physicians play a pivotal role in preventing, managing pediatric obesity and hypertension

Recent data show that weights of children in India’s upper socioeconomic classes have risen when compared with earlier reports, with a median weight at all ages of 4 kg more than children 2 decades earlier. This trend aligns with reports of increasing overweight and obesity in children across the world…. 

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Posted in Pediatrics, Primary Care | Tagged , , , , , , , | Volume: | Leave a comment

Anti-nausea agent ondansetron at 32-mg IV dosing may affect heart rhythm regularity

A single 32-mg intravenous (IV) dose of the anti-nausea drug ondansetron has been linked to increased heart rhythm irregularities, particularly QT-interval prolongation, according to a recent Drug Safety Communication issued by the United States Food & Drug Administration (FDA). Ondansetron is a very effective 5HT3 antagonist used in India and… 

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Low amounts of winter sunshine are associated with increased tuberculous meningitis incidence

Key Point: This study found a significant association between the monthly tuberculous meningitis incidence rate (a severe extrapulmonary complication of TB) and the number of sunshine hours 3 months earlier–possibly implicating vitamin D deficiency. Tuberculous meningitis (TBM) is a severe extrapulmonary complication of tuberculosis occurring mainly in early childhood, and… 

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Identifying factors that predict meningeal tuberculosis could improve outcomes

Among the various forms of tuberculosis (TB) affecting the central nervous system, meningeal TB is the most severe and has the highest mortality rate. A retrospective study conducted in South India focused on identifying factors that predict mortality to assist clinicians in treating these patients and formulating prognoses for them…. 

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Global cancer cases estimated to rise 75% by 2030

Cancer rates are on the rise worldwide and predicted in a recent study to increase by 75% to an estimated 22.2 million new cancer cases in 2030, compared with 12.7 million in 2008. In countries such as India, new cancer cases are predicted to rise slightly higher to 78%, while… 

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Posted in Non-Communicable Disease, Primary Care | Tagged , , , , , , , , , , , , , | Volume: | Leave a comment