Monthly Archives: May 2012

Thrombolysis may be beneficial later and in older patients suffering an acute stroke

About 1.44 to 1.64 million cases of new stroke occur each year in India, with stroke sufferers losing over 6 million disability-adjusted life years (DALYs) annually due to death and disability, according to data from the World Health Organization (WHO). Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is used to… 

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Posted in Geriatrics, Neurology, Neurology Featured 2, Non-Communicable Disease, Pharmacology, Primary Care | Tagged , , , , , , , , , | Volume: | Leave a comment

Even infrequent use of hypnotics may increase mortality risk

Taking hypnotic drugs, even sporadically, may increase the risk of death, a recent study has found. Researchers at the Scripps Clinic Sleep Center in La Jolla, California, United States, estimated the mortality risk of hypnotics in 10,529 adults who received hypnotic prescriptions and 23,676 matched controls; the subjects were followed… 

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Posted in Neurology, Neurology Featured 2, Pharmacology, Primary Care | Tagged , , , , , | Volume: | Leave a comment

Meta-analyses: Aspirin’s utility in chronic kidney disease isn’t clear

An increase in the risk of bleeding may nullify the benefits of antiplatelet therapy in patients with chronic kidney disease (CKD), according to a pair of meta-analyses. The evidence from clinical trials included in the meta-analyses is of low quality, the authors reported, with numerous limitations. “Bleeding hazards and lack… 

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Posted in Cardiovascular Disease, Diabetes, Nephrology, Pharmacology, Primary Care | Tagged , , , , , , , , | Volume: | Leave a comment

Controlled cord traction not essential in reducing risk of postpartum hemorrhage

Approximately one-quarter of all pregnancy- and delivery-related maternal deaths worldwide occur in India, most of which are caused by postpartum hemorrhage, according to the World Health Organization (WHO). WHO recommends Active Management of the Third Stage of Labor (AMTSL), which includes several components: Key Point: Controlled cord traction is not… 

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Posted in Ob/Gyn | Tagged , , , , | Volume: | Leave a comment

Early therapy delays progression to clinically definite multiple sclerosis

mdCurrent Conference Report: 64th American Academy of Neurology Annual Meeting Data from 2 major phase 3 trials have demonstrated that progression to clinically definite multiple sclerosis (MS) can be prevented or delayed with early rather than delayed therapy. Two regimens of subcutaneous interferon beta-1a (IFNb) were evaluated in patients who… 

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Posted in mdCurrent Conference Reports, Neurology, Pharmacology | Tagged , , , , , , , , , , | Volume: | Leave a comment

Pacemaker study examines whether Indians age earlier than Westerners

mdCurrent Conference Report: Heart Rhythm 33rd Annual Scientific Sessions Indians presenting for permanent pacemaker (PP) placement are younger than those in the Western population, according to results of a study presented at the 33rd Annual Scientific Sessions of the Heart Rhythm Society (HRS). Key Point: Indians present at a younger… 

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Posted in Cardiology, Cardiovascular Disease, Geriatrics, mdCurrent Conference Reports, Non-Communicable Disease, Primary Care | Tagged , , , , , , , , | Volume: | 1 Response

Continuous intestinal infusion of levodopa-carbidopa gel shows benefit in advanced Parkinson’s disease

mdCurrent Conference Report: 64th American Academy of Neurology Annual Meeting A novel strategy to reduce the motor complications associated with fluctuating blood levels of levodopa in patients with Parkinson’s disease was associated with clinically meaningful improvements in disease control, according to the authors of a double-blind trial. Undertaken in patients… 

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Posted in mdCurrent Conference Reports, Neurology, Pharmacology | Tagged , , , , , , | Volume: | Leave a comment
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